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Latest Publication and Research on Chemotherapy Drugs

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Emerg Med Int    

Current pharmacological advances in the treatment of cardiac arrest.

Papastylianou A, Mentzelopoulos S

Intensive Care Unit, Evagelismos Hospital, 45-47 Ipsilantou Street, Athens 10676, Greece.

Cardiac arrest is defined as the sudden cessation of spontaneous ventilation and circulation. Within 15 seconds of cardiac arrest, the patient loses c... Read More

Source: PubMed

  2011 Dec 5  

Metastatic adenoid cystic carcinoma of the salivary gland responding to cetuximab plus weekly paclitaxel after no response to weekly paclitaxel alone.

Caballero M, E Sosa A, Tagliapietra A, Grau JJ

Otorhinolaryngology Department, University of Barcelona. Hospital Clínic. IDIBAPS (Augusto Pi Sunyer Institute for Biomedical Research). mcaba@clinic.ub.es.

BACKGROUND: Adenoid cystic carcinoma (ACC) of the salivary gland frequently develops lung metastases. In cases in which chemotherapy is indicated, res... Read More

Source: PubMed

  2011 Dec 5  

Emergence of central nervous system myeloma in the era of novel agents.

Gangatharan SA, Carney DA, Prince HM, Wolf MM, Januszewicz EH, Ritchie DS, Harrison SJ

Peter MacCallum Cancer Centre, Melbourne, Australia. shane.gangatharan@gmail.com.

Although multiple myeloma (MM) remains an incurable disease, considerable improvements in survival have been made with the introduction of autologous ... Read More

Source: PubMed

Emerg Med Int    

Current pharmacological advances in the treatment of cardiac arrest.

Papastylianou A, Mentzelopoulos S

Intensive Care Unit, Evagelismos Hospital, 45-47 Ipsilantou Street, Athens 10676, Greece.

Cardiac arrest is defined as the sudden cessation of spontaneous ventilation and circulation. Within 15 seconds of cardiac arrest, the patient loses c... Read More

Source: PubMed

  2011 Dec 5  

Metastatic adenoid cystic carcinoma of the salivary gland responding to cetuximab plus weekly paclitaxel after no response to weekly paclitaxel alone.

Caballero M, E Sosa A, Tagliapietra A, Grau JJ

Otorhinolaryngology Department, University of Barcelona. Hospital Clínic. IDIBAPS (Augusto Pi Sunyer Institute for Biomedical Research). mcaba@clinic.ub.es.

BACKGROUND: Adenoid cystic carcinoma (ACC) of the salivary gland frequently develops lung metastases. In cases in which chemotherapy is indicated, res... Read More

Source: PubMed

  2011 Dec 5  

Emergence of central nervous system myeloma in the era of novel agents.

Gangatharan SA, Carney DA, Prince HM, Wolf MM, Januszewicz EH, Ritchie DS, Harrison SJ

Peter MacCallum Cancer Centre, Melbourne, Australia. shane.gangatharan@gmail.com.

Although multiple myeloma (MM) remains an incurable disease, considerable improvements in survival have been made with the introduction of autologous ... Read More

Source: PubMed

  2011 Dec 5  

Aerosolized Gentamicin Reduces the Burden of Tuberculosis in a Murine Model.

Roy CJ, Sivasubramani SK, Dutta NK, Mehra S, Golden NA, Killeen S, Talton JD, Hammoud BE, Didier PJ, Kaushal D

Divisions of Microbiology.

Tuberculosis (TB) is a major infectious disease problem. 1.8 million people annually die due to TB. Emergence of drug-resistant Mycobacterium tubercul... Read More

Source: PubMed

Cancer Control    

Treatment of relapsed or refractory chronic lymphocytic leukemia.

Veliz M, Pinilla-Ibarz J

Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL 33612, USA. Javier.Pinilla@moffitt.org.

Recent advances in the treatment of chronic lymphocytic leukemia (CLL) have moved beyond the traditional use of alkylating agents and purine analogs i... Read More

Source: PubMed

  2011 Dec 5  

New challenges in endpoints for drug development in advanced melanoma.

Ribas A, Hersey P, Middleton MR, Gogas HJ, Flaherty KT, Sondak VK, Kirkwood JM

Department of Medicine, Division of Hematology-Oncology, Jonsson Comprehensive Cancer Center, UCLA.

During the past three decades, the field of clinical research for the treatment of advanced melanoma lacked significant advances. Available drugs had ... Read More

Source: PubMed

  2011 Dec 5  

New challenges in endpoints for drug development in advanced melanoma.

Ribas A, Hersey P, Middleton MR, Gogas HJ, Flaherty KT, Sondak VK, Kirkwood JM

Department of Medicine, Division of Hematology-Oncology, Jonsson Comprehensive Cancer Center, UCLA.

During the past three decades, the field of clinical research for the treatment of advanced melanoma lacked significant advances. Available drugs had ... Read More

Source: PubMed

Drugs    

Pegylated Liposomal Doxorubicin: A Review of its use in Metastatic Breast Cancer, Ovarian Cancer, Multiple Myeloma and AIDS-Related Kaposi's Sarcoma.

Duggan ST, Keating GM

Adis, a Wolters Kluwer Business, Auckland, New Zealand.

Pegylated liposomal doxorubicin (Caelyx™, Doxil®) represents an improved formulation of conventional doxorubicin, with reduced cardiotoxicity and an i... Read More

Source: PubMed

Drugs    

Buprenorphine 5, 10 and 20?µg/h Transdermal Patch: A Review of its Use in the Management of Chronic Non-Malignant Pain.

Plosker GL

Adis, a Wolters Kluwer Business, Auckland, New Zealand.

This article reviews the pharmacology, therapeutic efficacy and tolerability profile of the 7-day lower-dose (5, 10 and 20?µg/h) buprenorphine transde... Read More

Source: PubMed

Drugs    

Triazole antifungal agents in invasive fungal infections: a comparative review.

Lass-Flörl C

Division of Hygiene and Medical Microbiology, Innsbruck Medical University, Innsbruck, Austria.

Invasive fungal disease continues to be a problem associated with significant morbidity and high mortality in immunocompromised and, to a lesser exten... Read More

Source: PubMed

Drugs    

Epigenetic-based therapies in cancer: progress to date.

Song SH, Han SW, Bang YJ

Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.

Epigenetic gene silencing is a hallmark of cancer cells. Two important types of epigenetic changes are DNA methylation and histone modification. These... Read More

Source: PubMed

  2011 Dec 5  

Aerosolized Gentamicin Reduces the Burden of Tuberculosis in a Murine Model.

Roy CJ, Sivasubramani SK, Dutta NK, Mehra S, Golden NA, Killeen S, Talton JD, Hammoud BE, Didier PJ, Kaushal D

Divisions of Microbiology.

Tuberculosis (TB) is a major infectious disease problem. 1.8 million people annually die due to TB. Emergence of drug-resistant Mycobacterium tubercul... Read More

Source: PubMed

Cancer Control    

Treatment of relapsed or refractory chronic lymphocytic leukemia.

Veliz M, Pinilla-Ibarz J

Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL 33612, USA. Javier.Pinilla@moffitt.org.

Recent advances in the treatment of chronic lymphocytic leukemia (CLL) have moved beyond the traditional use of alkylating agents and purine analogs i... Read More

Source: PubMed

Drugs    

Pegylated Liposomal Doxorubicin: A Review of its use in Metastatic Breast Cancer, Ovarian Cancer, Multiple Myeloma and AIDS-Related Kaposi's Sarcoma.

Duggan ST, Keating GM

Adis, a Wolters Kluwer Business, Auckland, New Zealand.

Pegylated liposomal doxorubicin (Caelyx™, Doxil®) represents an improved formulation of conventional doxorubicin, with reduced cardiotoxicity and an i... Read More

Source: PubMed

Drugs    

Buprenorphine 5, 10 and 20?µg/h Transdermal Patch: A Review of its Use in the Management of Chronic Non-Malignant Pain.

Plosker GL

Adis, a Wolters Kluwer Business, Auckland, New Zealand.

This article reviews the pharmacology, therapeutic efficacy and tolerability profile of the 7-day lower-dose (5, 10 and 20?µg/h) buprenorphine transde... Read More

Source: PubMed

Drugs    

Triazole antifungal agents in invasive fungal infections: a comparative review.

Lass-Flörl C

Division of Hygiene and Medical Microbiology, Innsbruck Medical University, Innsbruck, Austria.

Invasive fungal disease continues to be a problem associated with significant morbidity and high mortality in immunocompromised and, to a lesser exten... Read More

Source: PubMed

Drugs    

Epigenetic-based therapies in cancer: progress to date.

Song SH, Han SW, Bang YJ

Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea.

Epigenetic gene silencing is a hallmark of cancer cells. Two important types of epigenetic changes are DNA methylation and histone modification. These... Read More

Source: PubMed


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