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Ankylosing Spondylitis

Latest Publication and Research on Ankylosing Spondylitis

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  2011 Dec 5  

Enrichment of circulating IL-17-secreting IL-23 receptor-positive ?d T cells in patients with active ankylosing spondylitis.

Kenna TJ, Davidson SI, Duan R, Bradbury LA, McFarlane J, Smith M, Weedon H, Street S, Thomas R, Thomas GP, Brown MA

The University of Queensland Diamantina Institute, University of Queensland, Brisbane, Australia.

OBJECTIVE: Ankylosing spondylitis (AS) is a common inflammatory arthritis affecting primarily the axial skeleton. IL23R is genetically associated with... Read More

Source: PubMed

  2011 Dec 5  

Enrichment of circulating IL-17-secreting IL-23 receptor-positive ?d T cells in patients with active ankylosing spondylitis.

Kenna TJ, Davidson SI, Duan R, Bradbury LA, McFarlane J, Smith M, Weedon H, Street S, Thomas R, Thomas GP, Brown MA

The University of Queensland Diamantina Institute, University of Queensland, Brisbane, Australia.

OBJECTIVE: Ankylosing spondylitis (AS) is a common inflammatory arthritis affecting primarily the axial skeleton. IL23R is genetically associated with... Read More

Source: PubMed

  2011 Dec 6  

Aortitis in a patient with psoriatic arthritis.

Tufan A, Engin Tezcan M, Kaya A, Mercan R, Oner Y, Ozturk MA

Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Gazi University, 8.Kat, Besevler, 06500, Ankara, Turkey, dratufan@hotmail.com.

Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms. Inv... Read More

Source: PubMed

  2011 Dec 6  

Aortitis in a patient with psoriatic arthritis.

Tufan A, Engin Tezcan M, Kaya A, Mercan R, Oner Y, Ozturk MA

Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Gazi University, 8.Kat, Besevler, 06500, Ankara, Turkey, dratufan@hotmail.com.

Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms. Inv... Read More

Source: PubMed

Drugs    

Celecoxib: a review of its use for symptomatic relief in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

McCormack PL

Adis, a Wolters Kluwer Business, Auckland, New Zealand.

Celecoxib (Celebrex®) was the first cyclo-oxygenase (COX)-2 selective inhibitor (coxib) to be introduced into clinical practice. Coxibs were developed... Read More

Source: PubMed

Drugs    

Celecoxib: a review of its use for symptomatic relief in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

McCormack PL

Adis, a Wolters Kluwer Business, Auckland, New Zealand.

Celecoxib (Celebrex®) was the first cyclo-oxygenase (COX)-2 selective inhibitor (coxib) to be introduced into clinical practice. Coxibs were developed... Read More

Source: PubMed

  2011 Dec 2  

The prevalence of HLA-B27 in the United States: Data from the U.S. National Health and Nutrition Examination Survey, 2009.

Reveille JD, Hirsch R, Dillon CF, Carroll MD, Weisman MH

Division of Rheumatology, The University of Texas Health Science Center at Houston, 6431 Fannin, MSB 5.270, Houston, TX 77030. John.D.Reveille@uth.tmc.edu.

OBJECTIVE: To carry out the first large-scale population study of HLA-B27 prevalence in the United States, which is needed for public health planning ... Read More

Source: PubMed

  2011 Dec 2  

The prevalence of HLA-B27 in the United States: Data from the U.S. National Health and Nutrition Examination Survey, 2009.

Reveille JD, Hirsch R, Dillon CF, Carroll MD, Weisman MH

Division of Rheumatology, The University of Texas Health Science Center at Houston, 6431 Fannin, MSB 5.270, Houston, TX 77030. John.D.Reveille@uth.tmc.edu.

OBJECTIVE: To carry out the first large-scale population study of HLA-B27 prevalence in the United States, which is needed for public health planning ... Read More

Source: PubMed

  2011 Dec 4  

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis.

Lin Z, Bei JX, Shen M, Li Q, Liao Z, Zhang Y, Lv Q, Wei Q, Low HQ, Guo YM, Cao S, Yang M, Hu Z, Xu M, Wang X, Wei Y, Li L, Li C, Li T, Huang J, Pan Y, Jin O, Wu Y, Wu J, Guo Z, He P, Hu S, Wu H, Song H, Zhan F, Liu S, Gao G, Liu Z, Li Y, Xiao C, Li J, Ye Z, He W, Liu D, Shen L, Huang A, Wu H, Tao Y, Pan X, Yu B, Tai ES, Zeng YX, Ren EC, Shen Y, Liu J, Gu J

1] Department of Rheumatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. [2].

To identify susceptibility loci for ankylosing spondylitis, we performed a two-stage genome-wide association study in Han Chinese. In the discovery st... Read More

Source: PubMed

  2011 Dec 4  

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis.

Lin Z, Bei JX, Shen M, Li Q, Liao Z, Zhang Y, Lv Q, Wei Q, Low HQ, Guo YM, Cao S, Yang M, Hu Z, Xu M, Wang X, Wei Y, Li L, Li C, Li T, Huang J, Pan Y, Jin O, Wu Y, Wu J, Guo Z, He P, Hu S, Wu H, Song H, Zhan F, Liu S, Gao G, Liu Z, Li Y, Xiao C, Li J, Ye Z, He W, Liu D, Shen L, Huang A, Wu H, Tao Y, Pan X, Yu B, Tai ES, Zeng YX, Ren EC, Shen Y, Liu J, Gu J

1] Department of Rheumatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. [2].

To identify susceptibility loci for ankylosing spondylitis, we performed a two-stage genome-wide association study in Han Chinese. In the discovery st... Read More

Source: PubMed

  2011 Dec 3  

HLA alleles and drug hypersensitivity reactions.

Profaizer T, Eckels D

Histocompatibility and Immunogenetics Laboratory, University of Utah, Salt Lake City, UT, USA.

The human leucocyte antigen (HLA) system is well known for its association with certain diseases such as ankylosing spondylitis, celiac disease and ma... Read More

Source: PubMed

  2011 Dec 3  

HLA alleles and drug hypersensitivity reactions.

Profaizer T, Eckels D

Histocompatibility and Immunogenetics Laboratory, University of Utah, Salt Lake City, UT, USA.

The human leucocyte antigen (HLA) system is well known for its association with certain diseases such as ankylosing spondylitis, celiac disease and ma... Read More

Source: PubMed

Clin Invest Med    

Association of Interleukin-10 gene polymorphisms with ankylosing spondylitis.

Lv C, Wang Y, Wang J, Zhang H, Xu H, Zhang D

. phdzdl@yahoo.com.

Objective: Genetic polymorphisms of the Interleukin-10 (IL-10) promoter have been implicated in several autoimmune diseases, including seronegative sp... Read More

Source: PubMed

Clin Invest Med    

Association of Interleukin-10 gene polymorphisms with ankylosing spondylitis.

Lv C, Wang Y, Wang J, Zhang H, Xu H, Zhang D

. phdzdl@yahoo.com.

Objective: Genetic polymorphisms of the Interleukin-10 (IL-10) promoter have been implicated in several autoimmune diseases, including seronegative sp... Read More

Source: PubMed

  2011 Dec 1  

Associations of IL-23R polymorphisms with ankylosing spondylitis in East Asian population: a new case-control study and a meta-analysis.

Chen C, Zhang X, Li J, Wang Y

Department of Spinal and Neural Functional Reconstruction, China Rehabilitation Research Center, Beijing, China Department of Orthopaedics, Chinese PLA General Hospital, Beijing, China.

Interleukin-23 receptor (IL-23R) has been confirmed to be associated with ankylosing spondylitis (AS) in Caucasian. However, whether they are associat... Read More

Source: PubMed

  2011 Dec 1  

Associations of IL-23R polymorphisms with ankylosing spondylitis in East Asian population: a new case-control study and a meta-analysis.

Chen C, Zhang X, Li J, Wang Y

Department of Spinal and Neural Functional Reconstruction, China Rehabilitation Research Center, Beijing, China Department of Orthopaedics, Chinese PLA General Hospital, Beijing, China.

Interleukin-23 receptor (IL-23R) has been confirmed to be associated with ankylosing spondylitis (AS) in Caucasian. However, whether they are associat... Read More

Source: PubMed

  2011 Nov 29  

Early response to adalimumab predicts long-term remission through 5 years of treatment in patients with ankylosing spondylitis.

Sieper J, van der Heijde D, Dougados M, Brown LS, Lavie F, Pangan AL

1Department of Gastroenterology, Infectiology and Rheumatology, Charité Universitätsmedizin Berlin, Berlin, Germany.

OBJECTIVES: To describe the efficacy and safety through 5 years of adalimumab treatment in patients with ankylosing spondylitis (AS), and to identify ... Read More

Source: PubMed

  2011 Nov 29  

Early response to adalimumab predicts long-term remission through 5 years of treatment in patients with ankylosing spondylitis.

Sieper J, van der Heijde D, Dougados M, Brown LS, Lavie F, Pangan AL

1Department of Gastroenterology, Infectiology and Rheumatology, Charité Universitätsmedizin Berlin, Berlin, Germany.

OBJECTIVES: To describe the efficacy and safety through 5 years of adalimumab treatment in patients with ankylosing spondylitis (AS), and to identify ... Read More

Source: PubMed

  2011 Nov 29  

Golimumab reduces spinal inflammation in ankylosing spondylitis: MRI results of the randomised, placebo- controlled GO-RAISE study.

Braun J, Baraliakos X, Hermann KG, van der Heijde D, Inman RD, Deodhar AA, Baratelle A, Xu S, Xu W, Hsu B

1Rheumazentrum Ruhrgebiet, Herne, Ruhr-University, Bochum, Germany.

OBJECTIVE: To evaluate golimumab's effect on MRI-detected spinal inflammation in ankylosing spondylitis (AS).METHODS: Patients were randomly assigned ... Read More

Source: PubMed

  2011 Nov 29  

Golimumab reduces spinal inflammation in ankylosing spondylitis: MRI results of the randomised, placebo- controlled GO-RAISE study.

Braun J, Baraliakos X, Hermann KG, van der Heijde D, Inman RD, Deodhar AA, Baratelle A, Xu S, Xu W, Hsu B

1Rheumazentrum Ruhrgebiet, Herne, Ruhr-University, Bochum, Germany.

OBJECTIVE: To evaluate golimumab's effect on MRI-detected spinal inflammation in ankylosing spondylitis (AS).METHODS: Patients were randomly assigned ... Read More

Source: PubMed


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Posted by:  mini1184  Posted on: 01/23/2012
i am 27yrs of age...n have been diagnosed AS 4yrs back. i am taking Sulfasalazine regularly but the stiffness is increasing day by day....now i m having problem in breathing...i cant sleep properly and the capacity to do work is decreasing day by day..... Due to that pain some times i felt fever,fatigue,nausea.I have the pain in lumber,hip region,shoulder,chest pain,both legs and extreme pain in neck. And intake of medicines is causing gastroenteritis. please suggest something that can be more helpful..and how good is steam cell treatment.



Posted by:  nash21(Guest)  Posted on: 12/01/2010
hello, i m 4m pune. I am suffering by AS from last 8 years. I had concerned rheumatologist they had given me endomethacin tablets.Rite now i am taking the endomethacine medicines, physiotherapy and also doing the excersize regularly,but from last 3 months I have extream pain and I cant sleep properly in night for more than 3 hours. My age 24. I have the pain in lumber,hip region,shoulder,chest pain,both legs and extream pain in neck. Due to that pain some times i felt fever,fatigue,nausea. So please refer me something that will be helpful for me,so i will get pain relief. Thanks


Posted by:  patelcd(Guest)  Posted on: 06/30/2011
hi, came 2 know abt ur problem, i m patel c d, frm aurangabad practicing pranic healing, doing treatment on a person age 40 since 6 mnths, he is feeling better now, i suggest u 2 find a pranic healer in pune and get treated from them also...



Posted by:  arthritis-guy  Posted on: 11/06/2011
You are young to have ankylosing spondylitis this severe. Other drug options may not be any easier on you. Many patients find measurable relief from yoga or Pilates. Also many patients find some relief from omega e fatty acids.

Rusty





Posted by:  Nida_28(Guest)  Posted on: 08/08/2009
hi i m Nida...i m a patient of A.S.doctors suggest me to the surgery of hip joints replacment.i want to know that is it harmfull for me?my age is 25 now...


Posted by:  guest  Posted on: 07/12/2010
your age is only 25y.i suggest dat u go 2 the physiotherapy rehabilitation and do ex. regurely.



Posted by:  Chetan666  Posted on: 09/22/2011
I m also a sufferer of AS since past 5 years.I had a very bad condition I started swimming and it helped Me a lot.also dont do the surgery if it is not needed as I consulted it from a doctor.becoz ur age is still less increase ur span as much as u can and then do it when it is unbearable.it is a frank opinion




Posted by:  agrawalsantosh(Guest)  Posted on: 05/19/2009
Im a practising consultant in Paediatrics and would like to know the efficacy and safety of aceclofenac in active ankylosing spondylitis, the max duration of therapy



Posted by:  Ellen120  Posted on: 01/28/2009
Are there any doctors that specialize in Ankylosing Spondylitis? My brother has been told there is nothing that can be done! There has to be something or some doctor that can help him before he has no movement and can't breath any more. Please some one lead us to someone that can help us! Thanks, Ellen


Posted by:  satheeshgupta  Posted on: 03/08/2009
my doughter is suffering from Ankolysing spondylitis,i have given the treatment of cytotron,i have found some improvement,if you are intrested please contact me over mail for futher details.stheesh.



Posted by:  guest  Posted on: 08/19/2009
I am interested to know. How do I contact you. No details are available. By the way are yo a doc?



Posted by:  guest  Posted on: 02/03/2010
Hallo, i have read your views. i'm also suffering from this disease so i want to know about cytotron if possible plz. send me mail at



Posted by:  guest  Posted on: 07/15/2010
i m also suffered from a.s plz help me my age is only 22 plz help me. how do i contact u.



Posted by:  robin_kala  Posted on: 02/08/2012
i want to know about cytron



Posted by:  babadisco(Guest)  Posted on: 02/17/2010
try remicade but not 4 ever very speed reaction my brother also sufferring just like ur's brother uptill now no way. i m givein 1 syrub which had shown little effect




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