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Int J Alzheimers Dis Disturbed copper bioavailability in Alzheimer's disease. Kaden D, Bush AI, Danzeisen R, Bayer TA, Multhaup G Institute of Chemistry and Biochemistry, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany. Recent data from in vitro, animal, and human studies have shed new light on the positive roles of copper in many aspects of AD. Copper promotes the no... Read More Source: PubMed 2011 Dec 5 Amyloid precursor protein revisited: Neuronal-specific expression and the highly stable nature of soluble derivatives. Guo Q, Li H, Gaddam SS, Justice NJ, Robertson CS, Zheng H Baylor College of Medicine, United States. APP processing and Aß production plays a central role in Alzheimer disease (AD) pathogenesis. APP has been considered a ubiquitously expressed protein... Read More Source: PubMed 2011 Dec 6 Alzheimer disease: AD pathology-emerging subtypes or age-of-onset spectrum? Masliah E, Hansen LA Departments of Neurosciences and Pathology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0624, USA. ... Read More Source: PubMed Expert Rev Clin Pharmacol Insulin to treat Alzheimer's disease: just follow your nose? Schiöth HB, Frey WH, Brooks SJ, Benedict C Uppsala University, Department of Neuroscience, Uppsala, Sweden. Evaluation of: Craft S, Baker LD, Montine TJ et al. Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot c... Read More Source: PubMed Neurobiol. Aging The potential of functional MRI as a biomarker in early Alzheimer's disease. Sperling R Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Functional magnetic resonance imaging (fMRI) is a relative newcomer in the field of biomarkers for Alzheimer's disease (AD). fMRI has several potentia... Read More Source: PubMed Neurobiol. Aging Amyloid imaging as a biomarker for cerebral ß-amyloidosis and risk prediction for Alzheimer dementia. Klunk WE University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Since the introduction of amyloid imaging nearly 10 years ago, this technique has gained widespread use and acceptance. More recently, published repor... Read More Source: PubMed Neurobiol. Aging Recommendations for the incorporation of biomarkers into Alzheimer clinical trials: an overview. Morris JC, Selkoe DJ Departments of Neurology, Pathology, and Immunology, Knight Alzheimer Disease Research Center, Washington University, St. Louis, MO, USA. ... Read More Source: PubMed 2011 Dec 2 Sublethal doses of ß-amyloid peptide abrogate DNA-dependent protein kinase activity. Cardinale A, Racaniello M, Saladini S, De Chiara G, Mollinari C, de Stefano MC, Pocchiari M, Garaci E, Merlo D IRCCS San Raffaele Pisana, Italy; Accumulation of DNA damage and deficiency in DNA repair potentially contribute to the progressive neuronal loss in neurodegenerative disorders, includ... Read More Source: PubMed Int J Alzheimers Dis Disturbed copper bioavailability in Alzheimer's disease. Kaden D, Bush AI, Danzeisen R, Bayer TA, Multhaup G Institute of Chemistry and Biochemistry, Freie Universität Berlin, Thielallee 63, 14195 Berlin, Germany. Recent data from in vitro, animal, and human studies have shed new light on the positive roles of copper in many aspects of AD. Copper promotes the no... Read More Source: PubMed 2011 Dec 5 Amyloid precursor protein revisited: Neuronal-specific expression and the highly stable nature of soluble derivatives. Guo Q, Li H, Gaddam SS, Justice NJ, Robertson CS, Zheng H Baylor College of Medicine, United States. APP processing and Aß production plays a central role in Alzheimer disease (AD) pathogenesis. APP has been considered a ubiquitously expressed protein... Read More Source: PubMed 2011 Dec 6 Alzheimer disease: AD pathology-emerging subtypes or age-of-onset spectrum? Masliah E, Hansen LA Departments of Neurosciences and Pathology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0624, USA. ... Read More Source: PubMed Expert Rev Clin Pharmacol Insulin to treat Alzheimer's disease: just follow your nose? Schiöth HB, Frey WH, Brooks SJ, Benedict C Uppsala University, Department of Neuroscience, Uppsala, Sweden. Evaluation of: Craft S, Baker LD, Montine TJ et al. Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot c... Read More Source: PubMed Neurobiol. Aging The potential of functional MRI as a biomarker in early Alzheimer's disease. Sperling R Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Functional magnetic resonance imaging (fMRI) is a relative newcomer in the field of biomarkers for Alzheimer's disease (AD). fMRI has several potentia... Read More Source: PubMed Neurobiol. Aging Amyloid imaging as a biomarker for cerebral ß-amyloidosis and risk prediction for Alzheimer dementia. Klunk WE University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Since the introduction of amyloid imaging nearly 10 years ago, this technique has gained widespread use and acceptance. More recently, published repor... Read More Source: PubMed Neurobiol. Aging Recommendations for the incorporation of biomarkers into Alzheimer clinical trials: an overview. Morris JC, Selkoe DJ Departments of Neurology, Pathology, and Immunology, Knight Alzheimer Disease Research Center, Washington University, St. Louis, MO, USA. ... Read More Source: PubMed 2011 Dec 2 Sublethal doses of ß-amyloid peptide abrogate DNA-dependent protein kinase activity. Cardinale A, Racaniello M, Saladini S, De Chiara G, Mollinari C, de Stefano MC, Pocchiari M, Garaci E, Merlo D IRCCS San Raffaele Pisana, Italy; Accumulation of DNA damage and deficiency in DNA repair potentially contribute to the progressive neuronal loss in neurodegenerative disorders, includ... Read More Source: PubMed 2011 Nov 12 Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA. Lipid peroxidation generates reactive aldehydes, most notably hydroxynonenal (HNE), which covalently bind amino acid residue side chains leading to pr... Read More Source: PubMed 2011 Nov 12 Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA. Lipid peroxidation generates reactive aldehydes, most notably hydroxynonenal (HNE), which covalently bind amino acid residue side chains leading to pr... Read More Source: PubMed Encephale [The mental stress of the accompaniment in Alzheimer's disease]. Caron R, Caron L CRPMS Paris-VII, 52, rue de la Presqu'île, 59870 Marchiennes, France. Alzheimer's disease affects patients in time and space and all dimensions of emotional, cognitive and social life. It is, in return, an unprecedented ... Read More Source: PubMed Encephale [The mental stress of the accompaniment in Alzheimer's disease]. Caron R, Caron L CRPMS Paris-VII, 52, rue de la Presqu'île, 59870 Marchiennes, France. Alzheimer's disease affects patients in time and space and all dimensions of emotional, cognitive and social life. It is, in return, an unprecedented ... Read More Source: PubMed |
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