The condition arises due to a defect in the digestive enzyme called lactase. Children with lactose intolerance have diarrhea and may not gain weight. In adults the symptoms include abdominal bloating, cramps, diarrhea, flatulence, nausea, audible bowel sounds (borborygmi) and an urgent need to have a bowel movement. Diagnosis is based on symptoms. Avoiding lactose and supplementing lactase enzymes are the usual treatments.
75% of the world’s population is estimated to suffer the deficiency. Prevalence is higher prevalence among Asian, African, and South American persons.
Males and females are equally affected by lactose intolerance. Among adults, the age of presentation of intolerance is 20-40 years.
About 44% of the women with lactose intolerance regain the ability to digest lactose during pregnancy. The condition is associated with very little morbidity.
Latest Publications and Research on Lactose IntoleranceDairy intake, dietary adequacy, and lactose intolerance. - Published by PubMed
Optimizing lactose hydrolysis by computer-guided modification of the catalytic site of a wild-type enzyme. - Published by PubMed
Fructose and lactose intolerance and malabsorption testing: the relationship with symptoms in functional gastrointestinal disorders. - Published by PubMed
Optimization of water-in-oil-in-water microencapsulated ß-galactosidase by response surface methodology. - Published by PubMed
Dietary Proteins and Functional Gastrointestinal Disorders. - Published by PubMed