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Hyperthyroidism / Graves Disease

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What is Hyperthyroidism?

Hyperthyroidism is a condition in which the thyroid gland makes excessive amount of thyroid hormone.

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The thyroid gland is located in the lower part of the neck, below the Adam's apple. The thyroid gland produces the hormones thyroxine (T4)and triiodothyronine (T3), which regulate many aspects of our metabolism. It also affects the heart, muscles, bones and cholesterol.

Hyperthyroidism / Overactive Thyroid

Normal Thyroid Levels
TestFromUnits
TSH - Thyroid Stimulating Hormone 0.4 - 4.0mU/L (milliunits per litre)
FT4 - Free T4 (the active part of thyroxine) 9.0 - 25.0pmol/L (picomoles per litre)
FT3 - Free T3 (the active part of triiodothyronine) 3.5 - 7.8pmol/L (picomoles per litre)
A low TSH level with a high FT4 level and a high FT3 level indicate hyperthyroidism (over-active thyroid).

Many diseases and conditions can cause hyperthyroidism. Graves’ disease is the most common cause of hyperthyroidism.

Having too much thyroid hormone speeds up most of the things in the body. A person with hyperthyroidism may lose weight quickly, have a rapid heartbeat, sweat a lot, or feel nervous and moody. Some patients have no symptoms at all and hyperthyroidism is diagnosed accidentally.

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Hyperthyroidism can be easily treated with the help of anti-thyroid medications, radioactive iodine or surgery. Without treatment, hyperthyroidism can lead to serious complications of the heart and bone.

What are the Causes of Hyperthyroidism?

Many factors contribute to the development of hyperthyroidism. They include:
  • Graves’ disease
  • Multi-nodular goitre
  • Solitary thyroid nodule
  • Thyroiditis
  • Iodine induced i.e. due to excessive iodine
  • Taking large doses of thyroid hormone
  • Untreated hyperthyroidism can lead to high blood pressure heart failure, and thyroid storm.
Causes of Hyperthyroidism

What are the Symptoms of Hyperthyroidism?

Symptoms of hyperthyroidism include:
  • Goiter or an enlargement of thyroid gland in the neck.
  • Weight loss despite increased appetite.
  • Nausea and vomiting
  • Diarrhea
  • Breathlessness on exertion
  • Emotional liability
  • Increased sweating
  • Heat intolerance
  • Loss of hair
  • Menstrual disorders
  • Exophthalmos - A condition when the eyes have a straight look protruded unusually out.
  • Fatigue
  • Rapid or irregular pulse
  • Palpitations
  • Sleeping difficulty
Symptoms of Hyperthyroidism

How Do You Diagnose Hyperthyroidism?

Physical examination of the patient reveals:
  • Enlarged thyroid gland
  • Increased heart rate
  • Elevated systolic blood pressure
Clinical diagnosis does help, but biochemical diagnosis is confirmatory.

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Blood hormone levels of T3 and free T4 are elevated. The thyroid stimulating hormone (TSH) level is usually low.
Diagnosis of Hyperthyroidism

How Do You Treat Hyperthyroidism?

Thetreatment of hyperthyroidism depends on the cause and the severity of symptoms. Hyperthyroidism can be treated with one or more of the following:
  • Anti-thyroid drugs work best when the symptoms of hyperthyroidism are mild. These medicines do not always work. The patient has to take them at the same time every day. If they stop working, radioactive iodine is the next option.
  • Radioactive iodine is a common treatment and most people are cured after taking one dose. It destroys part of the thyroid gland and stops the excess production of hormones, but does not harm any other parts of the body.
  • Surgery to remove the thyroid gland. However, the patient is required to take thyroid hormone replacement pills for life time.
Treatment of Hyperthyroidism

Hyperthyroidism During Pregnancy

Human chorionic gonadotropin (HCG) hormone is produced during pregnancy. This hormone is detected through pregnancy tests. HCG hormone has mild thyroid stimulating effects as a result can cause some symptoms of hyperthyroidism.

Hyperthyroidism occurs in 10-20% of normal pregnant women.  Pregnancies complicated by uncontrolled hyperthyroidism may result in a higher incidence of:
  • Spontaneous abortion
  • Preterm labor
  • Low birth weight babies

How do You Prevent Hyperthyroidism?

Iodine intake in the form of supplements and foods should be avoided as it can worsen hyperthyroidism. Vitamin B12, zinc and iron-rich foods should be included in the diet because people with hyperthyroidism are more likely to suffer from these nutrient deficiencies. Excessive weight loss can be managed by taking protein rich foods such as salmon, nuts and legumes. When hyperthyroidism is not treated, it may lead to osteoporosis. Including calcium-rich foods such as dairy products can help prevent such complications. Following a healthy lifestyle by avoiding alcohol, quitting smoking and engaging in regular physical activities can help improve the overall health.
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I am having TSH level of 0.01 and have been diagnosed hyperthyroid. My doc prescribed thyroxin 50 for 3 months, another doc says that throxin is used in hypothyroid only please suggest whether i can take thyroxin 50 or not?

regards
shubhra goel
36 yrs

shubhra_goel Sunday, August 23, 2009
any mediclaim policies for preexisting disease thyroid
mymoms Friday, June 5, 2009
I HAVE BEEN HAVING HAIR COME OUT BY HANDFULS HERE LATELY. I AM ON 7.5 OF THYROID MEDICINE. COULD THIS BECAUSING MY HAIR TO DISAPPEAR?
S.C.L Saturday, May 30, 2009
what is making my hair come out by handfuls so all of a sudden?
S.C.L Saturday, May 30, 2009
is depression and anxiety also a symptoms of hyperthyroid? also memory loss like forgetfulness...
popeye Wednesday, February 11, 2009
what is the diet and excersice for hyperthiroid ?
manju.dongre Friday, December 5, 2008
Other causes of hyperthyroidism - toxic adenoma, carcinoma metastases, drug induced (amiadrone,iodine preparations), gestational thyrotoxicosis
zishanakhtar Sunday, November 9, 2008
What is high Tsh level? What is its treatment?
guest Friday, October 10, 2008
I have developed Hyperthyrodism, can I concieve now? will there be any problem ?
guest Monday, October 15, 2007
Please visit your doctor before considering this - u will need to be on medication
sunny1 Tuesday, July 15, 2008
let me know which is critical - Hypo or Hyperthyroid
guest Tuesday, September 25, 2007
both are critical, take thyroxine if hypothyroid
sunny1 Tuesday, July 15, 2008
Can i use herbalife products to loose weight with an underactive thyroid
guest Sunday, June 3, 2007

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