Age-related Macular Degeneration (AMD) is cited as the most common cause of visual impairment in people in the developed countries, above the age of 60. Recently there is more data available on the macular degeneration in people belonging to the developing nations such as China and India.
Macular degeneration destroys the macula, a part of the eye which is responsible for central vision. This vision is required to read, drive and see faces clearly.
Several causes such as age, smoking, genetics, nutrition have been implicated. The genetics of the condition is ill understood although apoE and its E4 variant is implicated.
In some people, the disease progresses so slowly that they hardly sense a change in their vision, while in others it can be faster. Regular check ups may help to detect the disease faster which in turn can help to provide treatments. These treatments can help to slow the disease progress but never to completely restore vision.