Banned Drugs / Drugs Banned in India / List of Banned Drugs
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A number of individual drugs as well as fixed dose combinations are banned in India. Drugs undergo rigorous testing before they are introduced into the market. They are first tested in animals and then in human beings during clinical trials. The efficacy as well as safety profiles of the drug are tested. In spite of this, some adverse effects of drugs appear only after the drug is used in the general population. These adverse effects are detected though a process of regular monitoring after the drug is released called pharmacovigilance. If the adverse effects are severe or the risks of using the drug outweigh the benefits, or if the drug is ineffective, the country may ban the drug or the Drug Company may itself voluntarily withdraw the drug. Some drugs may cause adverse effects only when combined with particular drugs. In such cases, only the fixed dose combination is banned and not the individual drugs. A number of single drugs as well as fixed dose combinations have been banned for manufacture, marketing and distribution in India. Some drugs banned in India are mentioned below: ![]() Fenfluramine and dexfenfluramine Fenfluramine and dexfenfluramine were used to treat obesity. They were widely used in slimming centers. However, they were withdrawn due to reports of diseases of heart valves, fibrosis of the heart and pulmonary hypertension. The combination of fenfluramine and phenteramine, another weight loss pill was particularly notorious for causing heart valve problems and sudden death. Rimonabant Rimonabant was particularly effective in causing weight loss. It inhibited the action of substances called cannabinoids in the brain. It has been withdrawn due to serious side effects like depression, suicidal tendencies and seizures. Sibutramine Sibutramine is a weight loss pill that has been recently banned since it caused heart related side effects. Astemizole and terfinadine Astemizole and terfinadine are antihistamines that were used to treat allergies. They were banned since they could cause a heart condition called polymorphic ventricular tachycardia and even death when used in high doses or with drugs like erythromycin, clarithromycin and ketoconazole. Phenformin Phenformin is an antidiabetic drug similar to metformin. It has been banned since it carries a high risk of lactic acidosis. Rofecoxib and valdecoxib Rofecoxib and valdecoxib were popular painkillers that were used for arthritis and other painful conditions. They resulted in pain relief without causing gastric side effects. However, they were withdrawn due to concerns of heart attack and stroke with their use. Rosiglitazone Rosiglitazone is a drug used in the treatment of type 2 diabetes. It has been banned due to an increased risk of heart attacks. Gatifloxacin Gatifloxacin is an antibiotic whose use as an oral and injectable drug has been recently banned in India. This is due to its risk for severe hyperglycemia or high blood sugar levels in the elderly. Tegaserod Tegaserod is a drug that is used to treat patients with irritable bowel syndrome with predominantly constipation. It was withdrawn from the market since patients taking this drug showed increased incidence of heart attack and stroke. |
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Posted by:
ManujMM(Guest)
Posted on: 08/30/2012 I support the article as it is one of the few articles to guide the 'state-misguided' citizens of this administratively neglected country. Yet I find it dificult to find out the names of the brands which contained Fenfluramine [Pondimin] and Dexfenfluramine (Redux). I feel that citizens in India are not only suffering of apathy by the State but sometimes the silence of the State, which is many a cases has been spelled differently as 'corruption'. Poor citizens are suffering because the governments wont take action on the murderous companies and our representatives being hand (dirty, bloody) in glove (of the corporates).
Time and again Indian citizens are tested like guinea pigs, most suffer to the last with their families in a state without healthcare insurance. Yet shameless heads claim to have made our country a super power e.g.; IT power: I fail to understand how can a country can be powerful in IT when it neither has a Operating System of its own and when it has yet to manufacture a hardware chip for a 'scientific calculator'?
I again request, if anybody knows to help me by disclosing the brands which contained which Fenfluramine and Dexfenfluramine. Many are sufferring heart fibrosis, PPH, ...it is for them to know, what exactly happened to them?
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Posted by:
p_datt
Posted on: 02/17/2011 Human aqueous Placental extract is a very effective drug. It contains several bioactive therapeutic molecules. We [the team of Indian Institute of Chemical Biology, an unit of CSIR India] are working for last 12 years with the extract the trade name is ‘Placentrex’ and identified different molecules with the potent therapeutic efficacy e.g. fibronectin type III like peptide, Bioactive NADPH, PDRNs , some other peptides with protease regulatory property etc. Banning this drug is a loss of a huge number of populations suffering from chronic, non-healing /diabetic wounds, burn injuries, surgical trauma etc. These research findings have been published in highly reputed international (Us and UK based) as well as national journals (ref Pubmed). It’s an Indian drug with a very good reputation in abroad like France, Switzerland, Korea etc. We have been invited several times in abroad (Europe, especially in France) to deliver lectures on ‘Placentrex’ research findings. We are still working with the drug. So far we have not found any adverse effect of the drug. Several clinical studies have also been done on it and these are also published in different peer-reviewed medical journals. Without knowing the rationality, efficacy and safety ‘Banning this highly reputed product of India’ is very much unethical. Banning of such a globally accepted drug must be reconsidered.
Posted by:
chakradhi(Guest)
Posted on: 02/17/2011 My strongest support is with the above comments. Research findings on indigenous human placental extract which is available at pubmed[www.pubmed.com]is very rational, based on extremely scientific foundation. Efficacy of the drug is unquestionable and it has been accepted by the global scientific community through several high rated international and National scientific journals. Banning of such a successful Indian formulation is a shame for the country itself. Through the research on this placental extract our country has been glorified several times. Without knowing the actual fact, banning the drug is a shameful as per my opinion. |
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Posted by:
Hafeez(Guest)
Posted on: 01/26/2011 can you please give the references for this artcle |