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Down syndrome

Causes

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Several studies have been carried out to find out why the condition occurs and what are the causes of Down syndrome.

The improper separation of chromosomes (non disjunction ) during gamete formation or meiosis is the cause of trisomy 21.Several studies have associated non –disjunction with increased maternal age(Hook and Lindsjo).

Down syndrome

Mosaicism in parents can also lead to DS children (Warburton, 1985).

Translocations involving the chromosome 21 can lead to a Down Syndrome child. This can be inherited from the parents or it can arise denovo during embryo formation.

It is not necessary for the entire chromosome 21 to be involved in a trisomy. Just a region of the chromosome, 21q22, present in three doses is enough for the development of DS phenotype.

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Posted by:  johncenawwe  Posted on: 04/18/2012
Yes, If we diagnosis the down syndrome at early stage we can improve the Longevity and Metformin also a good medicine in this same category who treats Type II diabetes and effective in weight loss treatment also.



Posted by:  sanjitta  Posted on: 08/23/2011
mr Ram, i am a new member,i found your words nothing is impossible in this fast developing world, gives me more confidence



Posted by:  Rammohan.R  Posted on: 06/10/2011
Physio therapy,speech therapy, occupational and behavioural therapies are needed to speed up the mile stones in the growth of DS children. Homoeo treatment also helps in improving their brain related functioning.DS children will be very affectionate and very cute. Treatment/therapies should be started as early as possible to get better results. Hope, a day will come, when Down Syndrome in children and adults will be permanently cured. Nothing is impossible in this fast developing world because of the technological innovations made possbile by computers etc.




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