History of Diphtheria
Diphtheria is otherwise called the 'Strangling Angel of Children' and was a dreaded common childhood illness. Statistics shows that in the 1920s there were an estimated 100,000 to 200,000 cases of diphtheria per year in the United States, with 13,000 to 15,000 deaths.
Effective vaccines were not developed until the discovery and development of sulfa drugs following World War II. But now it has re-emerged in the newly independent states of the former Soviet Union and in some other parts of the world at near-epidemic levels. The increases have generally been the result of failed public health and immunization programs in areas weakened by economic and social turmoil.
Latest Publications and Research on DiphtheriaLocal "On-Demand" Generation and Function of Antigen-Specific Foxp3+ Regulatory T Cells. - Published by PubMed
Analysis of novel iron-regulated, surface anchored, hemin-binding proteins in Corynebacterium diphtheriae. - Published by PubMed
Cost-benefit analysis of hospital based postpartum vaccination with combined tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap). - Published by PubMed
Lack of Association of Guillain-Barre Syndrome with Vaccinations. - Published by PubMed
Long term prevention of chronic allograft rejection by regulatory T cell immunotherapy involves host Foxp3-expressing T cells. - Published by PubMed