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Bleeding Disorders
Drugs For Bleeding Disorders
aminocaproic acid
anti-inhibitor coagulant complex- heat treated
antihemophiliac factor
aprotinin
carbazochrome
factor ix
fibrinogen concentrate
goserelin
oprelvekin
phylloquinone
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Bleeding Disorders
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Bleeding disorder is an acquired or an inherited condition, which is characterized by excessive bleeding in the persons affected by the disorder. In our body, blood circulates inside the blood vessels called the veins, arteries and capillaries. If there is a crack or damage of the vessel then bleeding occurs into the organs or externally.  Under normal conditions, our body resorts to its own mechanism to cope with bleeding through a process called hemostasis. During this process the blood vessels constrict to decrease blood flow and platelets in the blood accumulate to form a plug. This is then stabilized by a film of fibrin that forms a barrier. This barrier remains in place till the injury is fully healed. The process of clot formation, involving a range of clotting factors, occurs sequentially in a coagulation ‘cascade’. The clot is dissolved (fibrinolysis) once the wound is healed.
In people with bleeding disorders, the clotting process is impaired and this results in spontaneous bleeding. If a component that aids in clotting is missing, deficient or is dysfunctional then it results in excessive bleeding. The disorders are first detected during early childhood and the resultant bleeding can be very severe. Bleeding conditions do not have a permanent cure. They can, however, be managed. |
Latest Publication and Research on Bleeding Disorders - Updated on 04/18/2013.
Total Thyroidectomy for Multinodular Goiter. Possibility of Implementation in a District Hospital. - Published by PubMed
A chemically-modified inactive antithrombin as a potent antagonist of fondaparinux and heparins anticoagulant activity. - Published by PubMed
Procoagulant tissue factor-exposing vesicles in human seminal fluid. - Published by PubMed
Two cases of acquired haemophilia A associated with chronic myelomonocytic leukaemia. - Published by PubMed
Presentation, distribution pattern, and management of diverticular disease in a Nigerian tertiary hospital. - Published by PubMed
Total Thyroidectomy for Multinodular Goiter. Possibility of Implementation in a District Hospital. - Published by PubMed
A chemically-modified inactive antithrombin as a potent antagonist of fondaparinux and heparins anticoagulant activity. - Published by PubMed
Procoagulant tissue factor-exposing vesicles in human seminal fluid. - Published by PubMed
Two cases of acquired haemophilia A associated with chronic myelomonocytic leukaemia. - Published by PubMed
Presentation, distribution pattern, and management of diverticular disease in a Nigerian tertiary hospital. - Published by PubMed
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