This technique allows examining histologic sections within a few minutes of removing the specimen from the patient.
The quality of the tissue sections is not as good as those of the permanent section.
A skilled pathologist and a knowledgeable surgeon can work together to use the frozen section's rapid availability to the patient's great benefit.
The specimen is a liquid, or small solid chunks suspended in liquid. This material is smeared on a microscope slide and is either allowed to dry in air or is "fixed" by spraying or immersion in a liquid. The fixed smears are then stained, and examined under the microscope.