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Acute Myeloid Leukemia - Signs and Symptoms


AML - Symptoms and Signs

Many cases of AML are asymptomatic and may be accidentally detected. Very often the early symptoms are non-specific and may resemble those of a viral infection.

Most patients seek medical care due to an illness that may include fatigue, fever and recurrent infections, weight loss, night sweats, or bleeding. Patients are often sick only for days to weeks prior to seeking medical attention.

Children may present with the following symptoms:

  • Feeling of tiredness and lethargy due to anaemia
  • Bruises and bleeding
  • Infections
  • Aches and pains
  • Swollen lymph glands

The early symptoms will be non-specific and may resemble those of a viral infection, but when they continue the diagnosis of AML is clear. Many cases are asymptomatic and may be detected during routine lab tests.

Some of the generalized signs and symptoms include:

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  • Fever
  • Fatigue
  • Loss of apetite
  • Weight Loss
  • Shortness of breath on exertion
  • Anemia
  • Frequent infections
  • Easy bleeding /bruising
  • Pin –head sized spots under the skin due to bleeding(petechiae)
  • Joint /bone pain
  • Enlargement of spleen
  • Enlargement of lymph nodes, in some cases
  • Inflammation of the skin, in some cases
  • Swelling of gums
  • Tumor outside bone marrow, called chloroma, in rare cases
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