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Acute Lymphoblastic Leukemia - Incidence


Incidence of Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia (ALL) can occur at all ages. However, it is most common in young children and older adults.

The incidence of Acute Lymphoblastic Leukemia (ALL) in Children below 15 years is approximately 3-4 cases per 100,000 children.

The following are some of the highlights of ALL incidence-

  • ALL is more prevalent in developed countries than in the developing ones. The magnitude of the disease appears to correlate with the socio-economic status.
  • There are approximately 2,400 children and adolescents below 20 years of age who are diagnosed with ALL each year in the United States.
  • A gradual increase in the incidence of ALL has been observed in the last 25 years.
  • ALL is the most common cancer among children with a peak incidence of 4-5 years of age. It accounts for 23% of childhood cancers (children younger than 15 years).
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  • The incidence of ALL appears to be highest in Hispanic children; it is 3- fold higher for white children, aged 2-3 years, compared to black children of the same age
  • In adults, it is less common than Acute Myelogenous Leukemia (AML). In the United States, approximately 1000 new ALL cases occur in adults each year.
  • Only 20-40% of adults with ALL are cured with current treatment regimens
  • The highest incidence of ALL occurs in Italy, the United States, Switzerland, and Costa Rica
  • The annual rate of ALL occurrence is approximately 30 to 40 per million.
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