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Psoriasis
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Causes / Risk Factors |
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The causes of psoriasis are not clearly understood. Some believe it to be caused by the excessive growth and reproduction of the skin alone. Others believe that the disease is mediated by the immune system. According to the latter theory the T-lymphocytes migrate to the dermis of the skin and triggers the release of cytokines, which causes inflammation and elevates production of skin cells. Several studies have confirmed the excessive expression of proinflammatory cytokines, such as TNF-alpha, interleukins and interferon-gamma, in psoriatic patients What triggers this release still keeps everyone guessing! There appears to be a link between the environmental and genetic factors in the development of this disease. One third of people affected by psoriasis report a family history of the disease. Researchers have unearthed a psoriasis-associated gene loci and in the case of monozygotic twins, there is a 70% chance of one twin to develop the disease if the other twin has already developed the disease. In dizygotic twins the risk is around 20%. Although immunosuppressants can control psoriasis, the role of the immune system has not been thoroughly understood. However, the disease usually raises its head following stress (either physical or mental), a skin injury or streptococcal infection. Some of the other factors that can aggravate psoriasis are- • Climate change • Stress • Medications like - beta blockers ,lithium salt and antimalarials, • Certain infections • Smoking • Alcohol consumption • Obesity Environmental factors – Can be important in the reccurrence of psoriasis as it can get aggravated in winter due to the cold temperatures. Sunlight can be of benefit, but constant exposure is not advised. Sometimes in children, excessive sun can result in the disease flare ups. Drugs - Antimalarial drugs, beta-blockers used to treat high blood pressure, and lithium, a drug used to treat depression and bi-polar disorder, can worsen psoriasis in some individuals. Non-steroid anti-inflammatory (NSAID) drugs, such as ibuprofen or naproxen, used to manage pain and inflammation, can also aggravate psoriasis. The hormonal changes within the body of growing children can trigger the immune system and make the disease worse. Stress is an important factor that can trigger worsening of symptoms and cause psoariasis to flare up. During its episode the hormone adrenalin gets released in large amounts and this can stimulate the immune system, resulting in a flare ups. The cause of psoriasis seems to be multifactorial. Despite all the research advances its causes are not fully understood. Psoriasis affects only human beings and no such disease equivalent is seen among animals. |
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Posted by:
lin70(Guest)
Posted on: 01/26/2013 i have been trying to deal with this disease for years i tried treatments but gotten temporary results ,till i have heard of this i call a prayer answered someone visited me and told me just put male sperm and you will never see Psoriasis again and i had nothing to lose so i did and it worked yes the thought of it bothered me but as long as it works and it did natural medicine got rid of my psoriasis
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Posted by:
Rosali(Guest)
Posted on: 05/21/2012 Psoriasis is a common multi factorial, non-contagious, auto-immune skin disease. It affects adults and children in equal proportion.
The exact cause osof psoriasis is unknown. There is evidence of a genetic predisposition. A positive family history is often observed. Psoriasis, being an autoimmune disorder has autosomal dominant inheritance. People with dry skin are more likely to develop psoriasis than those with oily or well-moisturized skin.
There are many precipitating and aggravating factors so it keeps on recurring and becomes difficult to treat.
Combination of ayurvedic herbs and homoeopathic remedies gives good results. These remedies along with nutritional supplements acts on the body and balance the altered immune responses. These are 100% natural and safe, free from side effects and they are not habit forming.
Some of the frequently used remedies are C54 PSORAease formula and R65 Reckeweg PSORAease formula.
These remedies work by relieving inflammation and reducing the itching of the skin, softening your hardened skin, aidding shredding of silvery scales and working on the immune system making it less responsive to triggering factors.
Posted by:
kogunmakin
Posted on: 12/13/2010 Hello Everybody!!!
I am a 4th year medical student conducting a survey to study co-morbid psychiatric dysfunction in individuals with psoriasis and other skin conditions such as keloids. At this point, there are very few studies that have explored the psychiatric effects of keloids in affected individuals, while some studies have elucidated increased psychiatric dysfunction in individuals with other chronic dermatological
conditions such as psoriasis.
The purpose of this survey is to explore the psychiatric effects of keloids and compare it to that of psoriasis, and elucidate to the medical community that psoriasis and keloids can have more than cosmetic effects.
In order to conduct this study I am looking for individuals with OR without psoriasis who are willing to complete a 5 minute ANONYMOUS survey by visiting the link:
http://www.zoomerang.com/Survey/WEB22BJ37GD644
Once the link has been visited it will not allow you to re-vist the survey in order to ensure that each individual takes the survey only one time. So please only click the link if you are prepared to take the quiz, as it will not allow you to take it again.
Thank you all for your help.
Posted by:
dreemancall
Posted on: 08/15/2009 Today's the world is returning towards natural way of curing due to the harmful effects of today's chemical & synthetic medicines. People are deeply worried on this issue and also insisting to use natural way of curing to get health & security. Our psoriasis cure process is 100% |
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Posted by:
psoriasis89(Guest)
Posted on: 06/02/2009 What is psoriasis? What causes psoriasis? Is there a cure or treatment for psoriasis? Psoriasis is a skin condition, it is a disease, but it is not contagious. The name comes from the Greek word for "itch." It can be hereditary, caused by external influences (allergic reaction to foods or the environment) and sometimes stress. 4-5% of the population is known to be affected, and this number is growing. However, it is suspected that 1 in 5 people have some form of psoriasis either descripts or none descript. Once you have psoriasis, it is very likely you will have it for ever. It may go away, and come back. It might respond to various treatments, and it may not. Basically psoriasis is your body over producing skin cells. You have too many skin cells in one location which is why it often swells up, becomes dry and even flaky. It can often be very itchy, red, sore, cracked and very tender. Psoriasis usually affect the scalp, hands, stomach, knees, feet and elbows. It is linked to dandruff and unfortunately to some forms of arthritis.
Posted by:
poriasis
Posted on: 05/11/2009 Are you suffering from Psoriasis? More than 4.5 million adults in the United States have been diagnosed with psoriasis, and approximately 150,000 new cases are diagnosed each year. An estimated 20% have moderate to severe psoriasis. Psoriasis occurs about equally in males and females. Recent studies show that there may be an ethnic link. It seems that psoriasis is most common in Caucasians and slightly less common in African Americans. Worldwide, psoriasis is most common in Scandinavia and other parts of northern Europe. It appears to be far less common among Asians and is rare in Native Americans
Posted by:
pepe56(Guest)
Posted on: 03/03/2009 I had psoriasis for two years and negligently did not care. It affected my scalp and both elbows. Whenever I went I left dandruff spills and that started to be a problem and people started to notice and comment on my elbows' white patches. I went to see doctors and their prescriptions were expensive and did not work. Until I talked to the owner of a pharmacy. He told me to use Polytar liquid shampoo for scalp. I used it everyday and washed my hair and scalp with. I did not use any other shampoo. I also used it on both my elbows at the same time. I took some precautions not to use other bath soap on the affected area. That was a miracle the patches completely dissapeared on my elbows, but some tiny points remained on my scalp. 6 months later, it reappeared on my scalp (seems the residual points developped) and appeared on one elbow. Just now I am using polytar again and it is working again on my scalp and also on my elbow. I keep thinking that if somebody use liquid shampoo (e.g polytar) on the affected areas, and a tar soap instead of ordinary bath soap, psoriasis CAN be cured. The affected parts must be rubbed with the shampoo until the rashes dissapear, and the shin become clear reddish. Furthermore I personally think (although I did not use it) that just after the shampoo and until the next one, a parrafin application will soften and repair the skin until the next shampoo application. In fact, I also noticed that the psoriasis patches start to cure from the centre first and then towards the edges. The skin became clear and back to real NORMAL. I have just started treating the resurge (mid february 2009) and will be able to tell soon whether the shampoo worked this time also. If somebody can start a daily usage (with deeply working the lesions, then applying parrafin), he may also be able to tell whether it worked or no in his case. |