Despite the description of the
disease as early as 1868, there is no reliable treatment for the muscle
It is however possible to slow down the
disease progress and preserve
the muscle strength and joint function,
enabling the patient to walk and sit.
As DMD affects
nearly all the muscles of the body, a number of challenges have to be
faced by those involved in the treatment process. A multi-disciplinary
approach is needed for effective management of the disabling
Various forms of treatment involving light
weight braces and splints, physiotherapy, pulmonary therapy (breathing
support) and surgery can be instituted.
of a particular treatment largely depends on the clinical condition of
the patient and the doctor's discretion.
identification of the DMD gene, researchers have developed animal models
that mimic the disease. Such clinical experiments have now enhanced our
pre-existing knowledge regarding the
Active research is also being conducted to
examine if injection of normal muscle cells (from healthy patients) or
introduction of corrected form of the dystrophin gene into muscle cells
(gene therapy) would reverse the disease
With such hope-giving treatment modalities
on the horizon, a treatment for DMD is not so far.
Published on Apr 01, 2008 Last Updated on Apr 30, 2016