
The joint inflammation is caused by deposits of uric acid crystals in the joint fluid(synovial fluid) and joint lining (synovial lining). Intense joint inflammation occurs when the white blood cells engulf the uric acid crystals, causing pain, heat and redness of the joint tissues.
Gout is an hereditary disorder, the intrinsic element of which is an inborn instability of nuclein metabolism which may remain latent, but under the influence of extrinsic factors, infections, becomes manifest, as betokened by local inflammatory tissue reactions in joints or elsewhere the specific character of which is attested by the associated uratic deposition.
- Richard Llewellyn Jones Llewellyn, 1885 |
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The only difference; my pain goes straight up my leg (on the inner part kind of like running up my main artery). I can't bend my knee because the pain on the underside is horrible. I can't stand because the top of my foot is so swollen, red and "water logged" that I end up just sitting with my foot up for a good 5-10 days. Please tell me what questions I should ask my doctors.
Oh, PS- I have CKD/ stage 3 and Type 1 diabetes. I weigh 145lbs and am 5'7".