The course of HIV infection and disease progression may span for a decade.
Stages of HIV infections include:
1) Primary infection
2) Dissemination of virus to lymphoid organs
3) Clinical latency
4) Induction of HIV expression
5) Clinical disease
The duration between primary infection and progression to clinical disease averages about 10 years.
Death usually occurs within 2 years after the onset of clinical symptoms.
Following primary infection, viral replication occurs and the virus in blood (viremia) is detectable for about 8-12 weeks.
Virus is widely disseminated throughout the body during this time, and the lymphoid organs become affected.