Medindia » Consumer Health » Health Information » Albinism - Albinism - Incidence, Causes and Types

Albinism / Hypopigmentation / Albinos

Albinism - Incidence, Causes and Types

RSS Feeds   Text 
Statistics show that about 1 in 17,000 suffer from some form of Albinism. It is an inherited disorder of melanin pigment of the body and is known to affect animals too.

Albinism affects people from all races. This condition is known to affect mammals, fish, birds, reptiles, and amphibians. The ‘white leopard’ is a well known such example. The most common term for an individual affected by albinism is "albino".

Albinism is an inherited defect affecting melanin production and metabolism. And statistics show that about 1 in 17,000 suffer from some type of albinism.

There are two main categories of albinism:

Skin and Eyes affected (Oculocutaneous albinism - OCA) It is the most common form of albinism and affects the eyes, skin and hair. This in turn can be categorized into different types based on the specific gene involved.

In Type 1 albinism there is a defect in the metabolism of an amino acid called tyrosine that leads to failure in converting tyrosine to melanin. The conversion normally happens due to an enzyme called tyrosinase, however, if there is a defect in the enzyme it fails to happen.

In Type 2 albinism there is a defect in the "P" gene. In this type there is only minor defect in the pigmentation at birth.

However the most severe form of Albinism affects hair, skin, and eye (more specifically the iris of the eye) that they are white or pink. They also suffer from vision defects, usually myopia or short sightedness and require glasses.

There are some conditions in which there is only a specific area of the body that is affected by the condition. These include:

Ocular albinism type1 (OA1): In this condition the skin color is usually normal and eye color may be in the normal range. But close examination of the eye reveals that there is no pigment in the retina. It accounts for about 10 to 15% of the albinism cases. It can be inherited either by an X-linked or an autosomal recessive process.

Waardenberg syndrome: where there is only a small lock of hair on the forehead that is white and not pigmented or there maybe just one or both eyes (the iris) that has absence of pigment.

Chediak-Higashi syndrome: lack of melanin pigment all over the body with few areas being spared.

Tuberous sclerosis (white leaf macule): these are small localized areas of depigmentation.

Hermansky-Pudlak Syndrome or HPS: This condition is associated with a great range in degrees of pigmentation, from no pigmentation to almost normal coloring. Vision usually ranges from 20/60 to 20/200(normal vision is 20/20). People with HPS lack dense bodies in their blood platelets which are responsible for releasing clotting factors. It is a single-gene disorder inherited in an autosomal recessive manner. It is a form of albinism associated with a bleeding tendency (bleeding disorder) along with problems of lungs (lung fibrosis) and bowel diseases.


Share it!
Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters

Notify me when reply is posted
I agree to the terms and conditions
  
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.
Posted by:  shah1  Posted on: 12/20/2011
hi i m an allied health professional and doing my research on the visual outcome with different optical aids of albinos to enhance their activities of daily life so plz any of u if have informaation about albinism plz send it on my id



Posted by:  pink_y(Guest)  Posted on: 12/04/2011
Hi, I am an albinic girl. I am 29 years old. I am orried about if I marry a guy than shall I have a normal baby or an albenic. What are the risk factors. Please help


Posted by:  Jboyismyfriend  Posted on: 02/28/2012
Yeah, in Biology, I learned things such as Punnet Squares. If 2 capital A’s are in the genotype [AA], then they are not albino. If 2 lowercase a’s are in their genotype (aa), then they will be. If it is one of each (Aa), then they will not be albino, but they can pass it on to their kids. You have aa. Someone without albinism in their family at all is AA. If you marry that dude, your child will be Aa (they will not show albinism, but they can pass it on to their kids. If they marry someone with AA, the child will have a 50% chance of AA and a 50% chance of Aa ). If you marry someone with albinism in their family (Aa [actually, they could be AA also, but it is unlikely {it all depends on the parents}]) then your child will have a 50% chance aa (full albino) and a 50% chance Aa (pass it on to their children). Hope that helps. For more info, Google Punnet Squares.



Posted by:  reset(Guest)  Posted on: 04/23/2012
male cant pass any symptoms because, they are XY and only the X holds the phenotype. female are XX so they can pass the phenotype. also male that has it cant hide it, because there is only 1 X. the X holds the genes so female may get XA Xa and that hide the phenotype because there is another X with lower case a.




Posted by:  slinkey3(Guest)  Posted on: 11/01/2011
ok so im a freshmen and i wanted to know if albinism occures more in humans or animals



Posted by:  Alone  Posted on: 10/30/2011
Can anyone tell me will my children have albinism if i marry a girl whose father have albinism?


Posted by:  awesome(Guest)  Posted on: 11/13/2011
you can go to genetic counceling to see if your children have a chance of having albinism. its all in genetics.



Posted by:  Jboyismyfriend  Posted on: 02/28/2012
Yeah, just see 2 comments up [pink_y]. Or, just read what I commented here: Yeah, in Biology, I learned things such as Punnet Squares. If 2 capital A’s are in the genotype (AA), then they are not albino. If 2 lowercase a’s are in their genotype (aa), then they will be. If it is one of each (Aa), then they will not be albino, but they can pass it on to their kids. You have aa. Someone without albinism in their family at all is AA. If you marry that dude, your child will be Aa (they will not show albinism, but they can pass it on to their kids. If they marry someone with AA, the child will have a 50% chance of AA and a 50% chance of Aa ). If you marry someone with albinism in their family (Aa [actually, they could be AA also, but it is unlikely {it all depends on the parents}]) then your child will have a 50% chance aa (full albino) and a 50% chance Aa (pass it on to their children). Hope that helps. For more info, Google Punnet Squares.




Posted by:  kersisparkle(Guest)  Posted on: 09/05/2011
I have a new friend at school that has this. He is the sweetest boy ever and I swear he acts no different than any other teenage boy on this earth [: But I'm always afraid to talk to him about this stuff like asking him questions I basically pretend like I don't notice that he's a black kid that's white. So this was helpful


Posted by:  Alone  Posted on: 10/30/2011
I am planning to marry a woman whose father has albinism. Will i my children have albinism if I marry that woman though she does not have albinism.



Posted by:  Jboyismyfriend  Posted on: 02/28/2012
No. You have a 1 in 4 chance, though, that you child will have Aa, in which they can pass it on to their children. Otherwise, they will be AA, where they have not albinism at all. I think I just commented on you before.




Posted by:  nikta  Posted on: 08/09/2011
I and my cousine carry albinism gene and neither of us have albinism,is it possible to change one of our gene or is there a way that we can born a healthy baby?


Posted by:  Jboyismyfriend  Posted on: 02/28/2012
Not exactly sure I understand. You seem to carry Aa, so if you have a baby dude person with someone who is not related to albinos, your children will not have it. However, your baby dude people will have a 1 in 4 chance each that they will have the same traits that you do.



Posted by:  nikta  Posted on: 03/03/2012
ya i know what u say but we love each other and we want to marry.i heard that there is a way to replace defective gene with healthy gene.is it true?




Posted by:  YoJim(Guest)  Posted on: 02/08/2011
Albinos creep me out!


Posted by:  mrelucious(Guest)  Posted on: 02/09/2012
why do you have to say something as awful as that we are as human as you are the different is only that we are light skin




Posted by:  owleyez(Guest)  Posted on: 08/10/2010
you guys are alllllll idiots LOL Im a senior with albinism!! PWNNNNNNNNNNNNNNN



Posted by:  IOnlyMadeThisLoginToPostThisComment(Guest)  Posted on: 03/11/2010
Omygosh! I'm a freshman doing a project on albinism! I saw a picture of an albino peacock and it was gorgeous! well, I had better go and finish up with my project! :)


Posted by:  guest  Posted on: 03/15/2010
hahha wooooww mee too lol we are probly doing the same project and i thought the albino peacock was beautiful



Posted by:  guest  Posted on: 04/26/2010
im doing a project on albinism tooooo!! holy cow.



Posted by:  guest  Posted on: 05/11/2010
same here!!!! its so awesome



Posted by:  guest  Posted on: 05/12/2010
ALL OF US! WOWOW! [ and yeah, that peacock is absolutly beautifull]



Posted by:  guest  Posted on: 06/09/2010
Well we had someone doing this for a project for March, April, and May. I figured I would make the June person!



Posted by:  moonbeam.stardust(Guest)  Posted on: 12/13/2010
same here. but i'm in middle skool!




Posted by:  d_pennell(Guest)  Posted on: 02/09/2010
hi my name is Darean Pennell i live in lansing michigan and i am a freshman in high school. i am doing a paper on people with albinism and have found out alot of stuff. even though i am not ill i fill for any one who is and thank you for this infomation


Posted by:  guest  Posted on: 02/22/2010
hey! I'm a freshman doing a project on albinism too.
haha. just thought i'd point that out.



Posted by:  guest  Posted on: 02/24/2010
I am also doing a project, except I am a sophomore. Get owned.



Posted by:  guest  Posted on: 02/24/2010
im also doing a project but im a senior PWNED!



Posted by:  guest  Posted on: 03/01/2010
Hey, me too! High five!



Posted by:  guest  Posted on: 07/24/2010
it's very good topic.
im intrstd to this topic furture research for albunism



Posted by:  guest  Posted on: 03/08/2010
Oh ya. Well, I am a senior citizen in high school who has albinism. I win.



Posted by:  guest  Posted on: 03/22/2010
i own all of yall haha



Posted by:  guest  Posted on: 03/24/2010
eyyyy! ima freshman and im doin stuff about albinism too:p but im all confused



Posted by:  guest  Posted on: 03/28/2010
I think it is statistically proven that most [9/10] people who look up anything related to albinism are in high school or college



Posted by:  guest  Posted on: 04/02/2010
no Im in junior high



Posted by:  guest  Posted on: 04/06/2010
Sophmore oover heree



Posted by:  guest  Posted on: 04/26/2010
i'm a freshman doing a project on it toooo! how coooooolllllll are weeeeee!!



Posted by:  MTDezarr(Guest)  Posted on: 02/07/2012
Im a biologist, studying about this still you all have alot to learn young fellas.



Posted by:  tana.mon.hanna(Guest)  Posted on: 05/15/2012
i m am making a brochure for the local doctor surgery, i am also an albino with marfan syndrome. whatta mix..




View all Comments (20) 
X
Related Links
Birth Defect - Genetic
Skin Disorder
Skin Cancer
Astigmatism
Strabismus

Medwonders Health Network

Citing this Health Article
The information on Medindia is factual, unbiased and authentic. If you find the content useful - PLEASE INCLUDE A LINK TO THIS PAGE.

Highlight the text, right-click, and select “copy”. Paste the link into your website, email, or any other HTML document.

News on Albinism
* Is Albinism Treatment On The Anvil?
* Witch Doctors Butcher Tanzania's Albinos for 'Lucky Potions'
* Albinos in Burundi Take Refuge from Sorcerers and Organ Traders
Total News Item 3
Are you a member of Facebook? Become a fan of Medindia and get breaking news delivered to your Facebook page.