A new study has found that women who had high levels of certain chemicals in
their bodies experienced menopause two to four years earlier than women with
lower levels of the chemicals.
According to a news release, the study from Washington University School of
Medicine is the first to broadly explore the association between menopause and
individual chemicals on a large scale. Scientists analysed blood and urine
levels of 111 chemicals that are suspected of interfering with natural hormone
production and distribution.
Senior author Dr. Amber Cooper, an assistant professor of obstetrics and
gynecology, said, "Chemicals linked to earlier menopause may lead to an
early decline in ovarian function, and our results suggest we as a society
should be concerned."
Data examined from 1,442 menopausal women was nationally representative of a
population of almost 9 million menopausal women. Scientists used information
collected from 1999-2008 as part of the Centers for Disease Control and
Prevention's National Health and Nutrition Examination Survey. The survey
included 31,575 people.
None of the menopausal women included in the data used estrogen-replacement
therapies or had ovary-removal surgery. All had been tested for levels of endocrine-disrupting
Researchers said that they analyzed the women's blood and urine samples for
exposures to 111 mostly man-made chemicals, including known reproductive toxins
and those that take more than a year to break down. "These chemicals included
phthalates, which are found in plastics, common household items,
pharmaceuticals, and personal care products; phytoestrogens, plant-derived
estrogens; and dioxins/furans, industrial combustion byproducts," they added.
To avoid chemical exposure, scientists recommend microwaving food in glass
or paper containers rather than in plastic. According to them, it is also
important to study ingredients in cosmetics, personal care products, and food
packaging that are used daily.
The study was published in the journal PLOS ONE.