Researchers Create Bladder In The Lab

by Medindia Content Team on  April 4, 2006 at 9:34 PM Organ Donation News   - G J E 4
Researchers Create Bladder In The Lab
In what is being hailed as a milestone, researchers at the Wake Forest University in North Carolina have managed to create a bladder in laboratory conditions and what's more have implanted these bladders into seven children suffering from bladder disease. The research team led by Dr. Anthony Atala has published their experimental study in the online issue of The Lancet.

All the seven children in the study were suffering from a birth defect called spinal myelomeningocele, which means that the spines have not been properly fused after birth. This meant that the protruding nerves used to impinge on the bladder thus weakening it and leading to incontinence. The usual treatment in such cases in reconstructive surgery using tissue grafts from the patients' intestines. But this could expose patients to risk of kidney stones or even cancer. In the current study, researchers used the patients' own cells to create a bladder in the laboratory and then grafted the same onto the existing bladders so as to create a functionally better organ. Dr Anthony Atala, who led the team, said that he began working on tissue engineering processes about 16 years ago and implanted all seven children before he left Children's Hospital in Boston in 2004. "This is one small step in our ability to go forward in replacing damaged tissues and organs," Dr Atala said. "This is a small, limited experience, but it has enough follow-up to show us that tissue engineering is a viable tool that will allow us to tackle problems of similar magnitude." His team is currently working on 20 different organs and tissues in the laboratory.

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions
hello can you please give me urgent information im under wakefield hospit,had kidney remove and my bladder damage can u help
guest Wednesday, June 7, 2006

You May Also Like

View All