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New Therapy Discovered By Scientists For Cystic Fibrosis

by Medindia Content Team on  January 19, 2006 at 7:18 PM Research News   - G J E 4
New Therapy Discovered By Scientists For Cystic Fibrosis
A new therapy has been discovered by scientists for lung problems which are associated with cystic fibrosis that they say may reduce the use of antibiotics. Chronic lung damage is caused by cystic fibrosis which is a genetic disorder. The damage is caused by excessive amounts of sticky mucus built up in the lungs.
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The treatment developed by researchers at the University of North Carolina and the University of Sydney involves inhaling a salt-water aerosol solution almost twice as salty as the Atlantic Ocean, according to BBC News.

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This helps to cut damage by restoring a thin lubricant layer of water that normally coats airway surfaces. In healthy people, the water layer lining in the airways helps to clear away excess amounts of mucus by sweeping it up into the mouth where it can be swallowed.

But this water layer is missing in people with cystic fibrosis, so they are unable to prevent mucus from clogging up their lungs. Ultimately, this can lead to respiratory failure. The new therapy works by using salt to suck water from the lung tissues out on to their surface. The US team used the aerosol to treat a small group of cystic fibrosis patients. They found that it significantly improved mucus clearance, lung function and breathing symptoms.

The Australian team then applied it to another 164 patients for a longer period, almost a year. They found patients needed fewer antibiotics to treat lung infections and were more able to attend work or school.

Edited IANS
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