Genetic Code Of C.difficile Cracked

by Medindia Content Team on  December 15, 2005 at 2:24 PM Research News
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Genetic Code Of C.difficile Cracked
The Quebec strain of C.difficile's genetic code is reported to have been cracked by the researchers from the McGill University. This will enable faster diagnosis and treatment of the ailment which causes severe diarrhea, abdominal pain, and fever, according to the Jewish General Hospital's Dasval. The strain has caused infections to breakout in nursing homes and hospitals in Quebec. The search can now commence for the other antibiotic resistance genes and toxins which will enable a better understanding as to why this strain causes the severe disease.

The strain is reportedly responsible for similar outbreaks in parts of Europe and the US. Technology from the US was used for splitting the genome. It has also been responsible for about 200 deaths in Quebec, Sherbrooke, and Montreal during the
first half 2004. The Quebec strain is capable of resisting the fluoroquinolones group of antibiotics. Future outbreaks of the disease, which normally takes place during the winter months can be prevented by the cracking of the genetic code. The doctors will also be able to trace the changes in the bacterium which makes it stronger.

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