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Curcumin found to halt spread of breast cancer in mice

Saturday, October 15, 2005 at 2:12:10 PM

Cancer News

  
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Curcumin is the main ingredient of turmeric that gives curry its mustard-yellow color. Extracted from the roots of the curcuma longa plant, curcumin is a member of the ginger family. While it is not used in conventional medicine, it is widely prescribed in Indian medicine as a potent remedy for liver disorders, rheumatism, diabetic wounds, runny nose, cough and sinusitis.

Various studies have examined the carcinogenic effect and anti-cancer effects of turmeric and controversial data has been obtained. A recent study conducted on the effects of the pigment in animal models has been found to inhibit the metastasis to the lungs of mice specifically designed to develop breast cancer. The spice appears to work by inhibiting the action of a protein crucial in the progress of the tumor.

The nontoxic natural substance not only repelled progression of the disease to the lungs, but also appeared to reverse the effects of paclitaxel, a commonly prescribed chemotherapy for breast cancer. There exists a possibility that the long-term use of the drug can trigger spread of the disease over a long period of time. The protective effect of the pigment adds a new ray of hope to risks associated with breast cancer treatment.

The toxicity of Paclitaxel is believed to activate a protein, thereby inducing an inflammatory response and eventually leading to metastasis. Curcumin has been found to suppress this response, making it impossible for the cancer to spread.
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Medindia on Breast Cancer:
Other than skin cancer, breast cancer is the most common type of cancer among women. Breast cancer mostly occurs in women over the age of 50, and the risk is especially high for women over age 60. Breast cancer is also found to occur more often in white women than African American or Asian women.
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