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Calcitriol [Vitamin D] with combination of painkillers for cancer treatment

by Medindia Content Team on  September 7, 2005 at 3:38 PM Cancer News   - G J E 4
Calcitriol [Vitamin D] with combination of painkillers for cancer treatment
Professor David Feldman and his colleagues from the Stanford University School of Medicine have reported the results of their study in the journal Cancer Research. The result of the study has found that high doses of Vitamin D with pain killers were found to reduce the growth of cancer in patients with prostate cancer. The study result say that the combination of these two drugs reduces the growth of prostate cancer by 70 percent.
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Due to very impressive results, the research team has started a clinical trial to see if the approach also works in men. "There is great enhancement when the drugs are given together, using what we think is a safe dose in humans," Feldman said in a statement. "It's hard to make an exact comparison, as we are talking about cells in a dish and not a person." "We don't want the patient to think that if they take over-the-counter vitamin D, it will work in the same way," Feldman said.

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The research team is testing the effect of Calcitriol, which is a form of Vitamin D that is efficiently metabolized by the body and more effective than other Vitamin D pills and fortified milk. The researchers wanted to exploit the earlier research results of Calcitriol and pain killers in the treatment of cancer, the workers wanted to test the synergistic effect of combining both the drugs for cancer treatment.

In a tissue culture study involving tumor cells, the administration of calcitriol reduced the prostate cell growth by 25 percent and combining painkillers like ibuprofen and naproxen with calcitriol killed 70 percent of the prostate cancer cells.
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