Dutch researchers have published the results of their work linking mutations in BRAC2 gene leading to development of cancers in men, which was published in the Journal of Medical Ethics. Mutations in BRAC2 gene which was found to cause development of breast and ovarian cancer in women has now found to increase the risk of development of pancreatic and prostate cancers in men. The results of the study also confirmed the relation between BRAC2 mutations and increased risk of development of bone and throat cancers. People with BRAC2 mutated gene were seven times more likely to have pharyngeal cancer and eight times more likely to have pancreatic cancer than the general population. Male carriers were more than twice as likely to have prostate cancer.
Early diagnosis of prostate cancer is required for effective treatment has half of the men with prostate cancer dies before starting the treatment. Screening of men for mutated BRAC2 gene will provide effective and early treatment.