Protein causing spread of colon cancer identified

by Medindia Content Team on  August 7, 2001 at 3:05 PM Research News
RSS Email Print This Page Comment
Font : A-A+

Protein causing spread of colon cancer identified
Researchers at the Georgetown University Lombardi cancer center, New Orleans have identified and isolated a protein that they say, is responsible for the spread of colon cancer to the liver. The protein, called Pa 28 alpha, can also cause the spread of other cancers, according to lead investigator Justinian Ngaiza, a clinical fellow in hematology/oncology at Georgetown's Lombardi Cancer Center.

To isolate the protein, Ngaiza and colleagues took genes expressed by colon tumor cells grown in the laboratory and converted them into proteins. Thousands of different proteins were injected into the mice, and two, Pa28 being one of them, targeted the liver.

The investigators are now researching if these proteins are capable of being expressed in human tumour biopsies. This being successful, the next step would be to develop a drug to block the action of Pa 28 alpha.

They are also hoping to inject tumour cells into mice from which the protein has been removed, to check if the tumour cells still spread to the liver.


Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Cancer and Homeopathy Colo-rectal cancer - Management Colorectal Cancer Cancer Facts Cancer Colon Crohns Disease Diverticulosis and Diverticulitis Colon Polyps Health Screening for Women 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive