In a major breakthrough in the advancement of scientific technology, a new tool called meltMADGE can scan rare genetic mutation at a fraction of cost. It combines thermal ramp electrophoresis with microplate array diagonal gel electrophoresis.
The technology devised by Professor Ian Day from university of Southampton in collaboration with Bristol, University college London, British Heart foundation and Department of Health identified a mutant gene causing high, moderate cholesterol levels among 10,000 middle aged individuals.
AdvertisementThrough this technique one can identify rare genetic mutation in a population and identify gene level changes says professor Day. Although this research is at still at infancy treatment for diseases in future can be streamlined based on genetic profile of an individual.
Professor Day is exploring a combination of meltMADGE and endo VIIMADGE to identify variations in genes causing diseases currently.
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