It is possible to lose knee lubrication following an injury to the knee. This may lead to inflammations and arthritis.
Researchers from University of Rhode Island had identified a way to find out how much loss of lubrication had happened to a knee after a knee injury, in order to find out whether the injury may be a risk factor for arthritis.
Although knee injury is considered to be a risk factor for arthritis, it was not known whether changes in lubrication can positively or negatively damage the cartilages. The researches for the study had been able to quantify loss of lubrication of the knee. For this the researchers had taken the synovial fluid from the knee and had measured the lubricin. This is a substance that is produced naturally to protect the joints from any wear and tear.
Drawing parallels from animal study, researchers had found that this disappears completely in three weeks following the knee injury. In humans, the researchers had found that the body produces more of CII peptides when knee injury happens. This indicates that the injury had damaged the joint cartilage.
The researchers had developed a test that will quantify the exact breakdown of the lubricin after knee injury.
Reference: Arthritis & Rheumatism, June 2005