Researchers say adults suffering from the most common form of brain cancer might fare better with a combination of radiotherapy and chemotherapy than radiotherapy alone .
Based on findings of the study it was seen that most people with the type of cancer known as glioblastoma receive surgery to remove as much of the cancer as safely possible and then undergo radiotherapy. The current study compared 573 patients with glioblastomas who were randomized to receive either radiotherapy alone or radiotherapy in conjunction with the chemotherapy drug temozolomide (Temodal).
It was seen that about 85 percent of the patients had previously undergone surgery to remove as much of the tumor as possible without significantly affecting functioning areas of the brain and all patients were treated early in the course of their disease. It was also seen that patients who received both radiotherapy and chemotherapy were more likely to survive at a two-year follow-up about 26 percent vs. about 10 percent. Median survival at 28 months was about 15 months for patients who received radiotherapy and chemotherapy compared to about 12 months for those who received radiotherapy alone.
Thus in conclusion researchers say their results suggest that the combination treatment warrants more study as the challenge remains to improve clinical outcomes further.