Medindia

X

Circumcision Found To Prevent HIV Spread

by Medindia Content Team on  January 7, 2004 at 2:49 PM General Health News   - G J E 4
Circumcision Found To Prevent HIV Spread
HIV is a virus that infects and destroys T-cells in the immune system. According to the Centers for Disease Control and Prevention, there are between 800,000 and 900,000 people living with HIV.
Previous research has shown circumcised men are less likely to be infected with HIV, and a new study helps explain why.
Researchers examined tissue samples from nine specimens of human foreskin. They found each sample contained cells expressing the protein DC-SIGN, which contains receptors that make it easier for HIV to enter cells, indicating foreskin may play a key role in disease transmission.
Advertisement

Researchers say their study was limited as biopsies of the penis are rarely taken, and most studies to date have used material from circumcisions. However, if human tissue were available, population studies correlating levels of DC-SIGN expression in the penis with HIV transmission rates could provide crucially important data. Researchers say these types of studies should be performed in both circumcised and uncircumcised men.

Advertisement
In conclusion researchers say their study results suggest that the human foreskin is important in mediating the sexual transmission of HIV and that the DC-SIGN may contribute to HIV transmission in the foreskin by enabling the infection of permissive cells.
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All