Erroneous Laboratory Operation May Lead To a Cancer Drug

by Jyothsna on  February 5, 2007 at 11:17 AM Cancer News
RSS Email Print This Page Comment
Erroneous Laboratory Operation May Lead To a Cancer Drug
An error in the laboratory may pave way to the discovery of a new drug for cancer. This was disclosed by Katherine Schaefer of Rochester University Medical Center. This may be a foundation study for treatments associated with colon, skin, liver and oesophagal cancers.
Advertisement

Schaefer was studying to locate therapeutic measures for swelling in Crohn's disease and ulcerative colitis which results in intense pain and diarrhoea. Cancer cells were used as controls for this study and a compound by the name PPAR-gamma modulator was being tested. Schaefer realized that a small error in her laboratory calculation resulted in the death of the cancer cells.

Advertisement
She also found that PPAR-gamma had killed all the epithelial lining of the tumor cells. In the mice this compound killed colon tumor with no side effects.

According to Schaefer, mode of action of PPAR-gamma is different from the current drugs. It attacks a section of cell cytoskeleton called tubulin. While tubulin is involved in building the cell arrangement, PPAR-gamma breaks it down. This indirectly indicates that the gamma compound could actually counter the effect of tumor cells to chemotherapy.

Schaefer also intends to pursue this study further and conduct more trials with mice on the same subject.

Source: Medindia
JYT
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Drug Toxicity Cancer and Homeopathy Signature Drug Toxicity Cancer Facts Cancer Common Lifestyle Habits that Cause Diseases Health Benefits of Dandelion Plant 
Advertisement

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive