A latest research finding reveals that there may exist a link between Vitamin A and gullet cancer. This study was conducted by Dr. Rebecca Fitzgerald of Medical Research Council Cell Unit and her team.
Gullet or Oesophageal Adenocarcinoma is caused due to the malformation of the oesophageal lining. This condition is also called as Barrett's oesophagus where the normal scaly lining of the oesophageal wall is slowly changed to glandular lining. The reason for this condition was not known till date.
But the team led by Dr Fitzgerald has found out that exposure to Vitamin A triggers the change in the oesophageal lining which was reversed when treated with Vitamin A inhibitors. According to this finding, the change in cell structure can be seen below the top layer of cells too.
Oesophageal Adenocarcinoma is one of the common forms of oesophageal cancer and in the United Kingdom alone around 7500 people are affected by this disease every year which has a near 100% mortality rate.