Higher Risk of Premature Menopause in Twins

by Gayatri on  October 25, 2006 at 12:06 PM Women Health News   - G J E 4
Higher Risk of Premature Menopause in Twins
According to a recent study, women with a twin are at upto 5 times higher risk of suffering from premature menopause than those without one.

The study was conducted on over 800 pairs of twins in the UK and Australia. The risk of premature ovarian failure (POF) at the age of 40 was 3-5 times higher in twins than women from the general population. POF causes the ovaries to shut down ten years or earlier than the usual period. Only 1-in-100 women get affected by ovarian failure in the under-40 category.

The U.S. scientists carried out an analysis of the data from 404 UK and 428 Australian twin pairs with natural menopause and compared it with a control group of 3,483 Dutch women enrolled for a breast-screening programme. In the control group, most of them reached menopause in their early 50s.

Professor Roger Gosden, of Cornell University, New York, who led the investigation, said: "Our study validates the hypothesis that twins have a statistically significantly higher prevalence of POF than women generally.

"The differences were large, at three to five-fold at both the 40 and 45-year threshold, and were similar in both the national registers."

Source: Medindia

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