Medindia

X

High Testosterone Destroys Nerve Cells

by VR Sreeraman on  September 30, 2006 at 4:42 PM Research News   - G J E 4
High Testosterone Destroys Nerve Cells
Recent studies conducted by Yale School Of Medicine have shown for the first time that excessive use of androgens or steroids to enhance muscle mass or for replacement therapy, which results in high levels of testosterone in the body can lead to a appalling loss of brain cells.
Advertisement

High intake of androgens, or steroids was previously proven to cause hyper excitability, volatile and violent nature, and suicidal tendencies. According to Barbara Enriches, the professor of Pharmacology and physiology, and senior author such behavioral patterns may be an evidence of changes in neurological functions modified by steroids used.

Advertisement
To quote Prof. Ehrlich,""Next time a muscle-bound guy in a sports car cuts you off on the highway, don't get mad, just take a deep breath and realize that it might not be his fault,".

The key male hormone testosterone plays elemental roles in development, differentiation, and cellular growth. In nerve cells testosterone functions as a neurosteroid and can bring on changes at the cellular level, as a consequence of which, changes in behavior, mood and memory are brought about. Neurodegenerative effects and neuroprotective role of androgens have now been noted.

The studies conducted have revealed that excessive doses of testosterone can automatically commence cell death in culture of nerve cells. Apoptosis or cell death is vital in various life processes, which is inclusive of development as well as disease.

Source: Eurekalert
SRM
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions
Will to high of levels of testosterone effect your body? My husband had low testosterone and is having to take Rx injections and we want to know if his levels get too high will it hurt him. Thank you
guest Sunday, October 1, 2006

You May Also Like

Advertisement
View All