The results of a new study shows that people with metabolic syndrome are significantly more likely to develop heart failure in middle age, the results of a new study indicate.
Metabolic syndrome means a cluster of conditions, including obesity, high blood pressure and low levels of 'good' (HDL) cholesterol. A person with this syndrome is at an increased risk of developing coronary artery disease, stroke and diabetes. A team of Swedish researchers for their studies monitored regularly over 2,300 men, who were aged 50 between 1970 and 1974. They kept a track on the men until they turned 70.
They said that those with metabolic syndrome at the start of the study were much more likely to go on to develop heart failure. In fact, they explained that those with the syndrome were almost twice as likely to develop heart failure when compared to those who did not have the syndrome.
They explained that the results were irrespective of any other risk factors for heart failure, such as smoking and a previous heart attack. The researchers are of the opinion that metabolic syndrome may directly affect the heart itself, as well as boosting the build up of fatty deposits in the arteries.
Dr. Erik Ingelsson, from Uppsala University in Sweden, and colleagues note, conducted the research. They said that the results show that the metabolic syndrome provides important risk information beyond that of established risk factors for heart failure. They explained that the likely mechanism is insulin resistance and the subsequent excess insulin circulating in the blood. They further said that insulin might excessively enlarge the heart muscle, so as to impair its capacity.
If these findings are confirmed, the researchers conclude, the metabolic syndrome may have direct effects on the heart, in addition to an increased risk of atherosclerosis.