Medindia

X

Use of Antioxidant Beta-carotene is Safe For Treating Prostate Cancer

by VR Sreeraman on  June 3, 2012 at 7:14 PM Research News   - G J E 4
Despite past safety concerns, the antioxidant supplement beta-carotene, is safe to use during radiation therapy treatments for prostate cancer and does not increase the risk of prostate cancer death or metastases, according to a study.
 Use of Antioxidant Beta-carotene is Safe For Treating Prostate Cancer
Use of Antioxidant Beta-carotene is Safe For Treating Prostate Cancer
Advertisement

The use of vitamin supplements and antioxidants is common, but the safety of using antioxidant supplements during radiation treatments for prostate cancer is controversial.

Advertisement
Radiation therapy relies on the pro-oxidant effects of DNA, which involves damaging tumor cells while leaving normal cells unharmed. However, some scientists have suggested that supplemental antioxidants may weaken the oxidizing effects of radiation and potentially lead to cancer recurrence.

In the largest study to date of its kind, researchers followed 383 prostate cancer patients who were randomized to receive beta-carotene or placebo to determine if antioxidants could potentially counteract the pro-oxidant effects of radiation therapy and increase a patient's risk of death or metastases.

The primary endpoint was prostate cancer death or bone metastases. Researchers found no significant differences in lethal outcomes among the patients who took the antioxidant beta-carotene versus those who did not.

"This study shows that antioxidant supplementation with beta-carotene during radiation therapy does not appear to detract from the benefit of radiation therapy."

Danielle Margalit, MD, MPH, lead author of the study and a radiation oncologist at the Dana-Farber Cancer Institute in Boston, said. "It also suggests that patients may continue to eat a well-balanced diet that contains foods with natural sources of antioxidants at the recommended daily amount."

Source: Eurekalert
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All