About Gout
High levels of uric acid in blood and recurring attacks of joint inflammation are the main symptoms of gout. Lifestyle changes like weight loss, increasing fluid intake and dietary changes can help.
High levels of uric acid in blood and recurring attacks of joint inflammation are the main symptoms of gout. Lifestyle changes like weight loss, increasing fluid intake and dietary changes can help.
‘Hyperuricemia and gout stimulate the immune system and activate inflammatory markers which trigger renal disease.’
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The common patho-physiological link appears to be the chronic, low-grade, systemic inflammation that is intrinsic to both conditions, and that may explain some of the perplexing observations noted in these clinical conditions. This thematic issue discusses the effect of the activation of the innate immune system, through stimulation of the NLRP3 inflammasome, leading to the subsequent generation of interleukins and the release of cytokines and chemokines, and how these factors interact in the complex interplay between hyperuricemia, gout and kidney disease.
Gout and Diet - Dietary Intervention - Reference
In gout excess of uric acid appears in the blood and its particles are deposited in joints as tophi.
In gout excess of uric acid appears in the blood and its particles are deposited in joints as tophi.
Aicardi-Goutieres Syndrome - Causes, Symptoms, Diagnosis, Treatment
Aicardi-Goutieres Syndrome is observed in infants and older children. To date, defects in 6 genes are known to cause the syndrome. Irritability, erratic sleep, and fever are some symptoms.
Aicardi-Goutieres Syndrome is observed in infants and older children. To date, defects in 6 genes are known to cause the syndrome. Irritability, erratic sleep, and fever are some symptoms.
Risk of Kidney Stones Increases With Obesity, Diabetes, and Gout
Risk of kidney disease has almost doubled since 1994 in American people and the researchers from the UCLA think that it is directly connected with the rise in metabolic syndrome.
Risk of kidney disease has almost doubled since 1994 in American people and the researchers from the UCLA think that it is directly connected with the rise in metabolic syndrome.
