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University of Toronto Researchers Shed Light on How Damaged DNA is Repaired

by Bidita Debnath on  July 25, 2015 at 11:39 PM Research News   - G J E 4
In a breakthrough discovery, Karim Mekhail, a professor at the University of Toronto has revealed how a damaged DNA is transported within a cell and repaired. By using yeast cells, researchers discovered the DNA ambulance, which is a motor protein complex.
 University of Toronto Researchers Shed Light on How Damaged DNA is Repaired
University of Toronto Researchers Shed Light on How Damaged DNA is Repaired
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His team also found that the DNA hospital, also known as the nuclear pore complex, repairs damaged DNA inaccurately. Mekhail said that this process allowed the cells to survive an injury, adding that the cell has a compromised genome, but is stable and could be replicated, which was usually a recipe for disaster.

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The implications of the research could extend to a large number of developmental and disease settings, including unraveling secrets of how cancer operates. The study has been published in Nature Communications.

Source: ANI
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