The creation of a new Biogenerator
stem cell device will aid broken heart. The device has the ability to hold the
stem cells produced from adult bone marrow cells. It can be affixed to the heart
wall or using a catheter, it can be injected into the cardiac tissue.
New myocytes are produced with
motivation got from release of proteins and growth factors straight in to the
heart. Explanting the Biogenerator at any time can help removing the stem cells.
The creator's foresee that hearts damaged by infarcts have the option of
"Our nanofibrous scaffold will
ensure that the therapeutic benefit provided by stem cells will be localized
directly to the damaged area of the heart," said NuVascular Technologies
founder and Chief Technical Officer Matthew Phaneuf. "This scaffold will
also prevent the cells from leaving the target area while permitting easy
removal of the device, if required. We are confident that our devices can
provide a minimally invasive, highly effective treatment for heart disease that
can actually reverse the damage rather than providing a temporary solution that
often comes with complications."
Reports reveal that, in the US,
heart failures affect more than a 5 million people. The cost incurred as a
result totals to $39.2 billion per year. The most common heart disease reported
till date is the coronary heart disease. This mostly causes permanent damage to
a portion of the heart muscle. Also, the hearts ability to pump blood
decreases. Heart muscles do not have the ability to proliferate and regenerate
on their own nor do they have the ability to repair themselves. Though this may
be the theory, recent medical sciences and research promises that the heart
bears ability to regenerate.
"Our research has given every indication
that these devices could be revolutionary in repairing heart damage and
treating heart failure," said Dr. Glenn Gaudette, Associate Professor,
Department of Biomedical Engineering at WPI. He has also been working with
BioSurfaces, Inc. on the discussed technology for over six years. "While cells
contained in the scaffold of the nanofibrous material cannot escape, oxygen and
molecules can move through the nanofibrous membrane to stimulate the cells
within the damaged heart."