A brief communication published online October 12 in the Journal of the National Cancer Institute has revealed that inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas.
Aspirin has been shown to prevent the recurrence of colorectal polyps, but it's not clear how it works. One hypothesis is that it may affect the levels of substances, such as C-reactive protein and others, that are markers of inflammation.
Colorectal Cancer - Types, Causes, Risk Factors, Symptoms, Diagnosis, Treatment, Prognosis & Prevention
Colorectal cancer is a cancer that starts in the colon or the rectum. Colorectal cancer is the third most common cancer in men.
Colorectal cancer is a cancer that starts in the colon or the rectum. Colorectal cancer is the third most common cancer in men.
Changes in levels of all five inflammation markers were not associated with adenoma recurrence. For those who did not receive folic acid, C-reactive protein levels in those in the 325 mg/d aspirin group changed very little, whereas it was statistically significantly increased in the placebo group. For subjects who received folic acid, the reverse association was observed.
"Our data suggest that low dose aspirin has modest effects on stabilizing [C-reactive protein], which may be abrogated by a high level of folate," the authors write. "However, such beneficial effects do not appear to confer protection against colorectal neoplasia. Inflammation markers do not mediate the previously observed effects of aspirin and folic acid on colorectal adenomas."
Colo-rectal Cancer - Management
Treatment for Colorectal Cancers may involve surgery,chemotherapy, radiation therapy or biological therapy. Some people require a combination of treatments.
Treatment for Colorectal Cancers may involve surgery,chemotherapy, radiation therapy or biological therapy. Some people require a combination of treatments.
Source-Eurekalert
RAS
Colorectal Cancer Screening Could Cut Costs Even as Treatment Costs Increase
A new study in the Journal of the National Cancer Institute has revealed that investing in some colorectal cancer screening programs could cut expensive treatment costs
A new study in the Journal of the National Cancer Institute has revealed that investing in some colorectal cancer screening programs could cut expensive treatment costs
Women Fare Better Than Men With Metastatic Colorectal Cancer
Younger women with metastatic colorectal cancer lived longer than younger men. However, this survival advantage disappeared with age.
Younger women with metastatic colorectal cancer lived longer than younger men. However, this survival advantage disappeared with age.
