Antiepilectic drug treatments given during brain development could trigger schizophrenia-like behaviour,researchers at Georgetown University Medical Center have found.
A history of seizures during infancy leaves a person at significantly higher risk of developing schizophrenia later in life, but researchers aren't sure whether the seizures themselves or the drugs used to treat them are to blame.
About Schizophrenia
Schizophrenia is a mental disorder characterized by symptoms of thought, behavior and social problems.
Schizophrenia is a mental disorder characterized by symptoms of thought, behavior and social problems.
Animal models that received AEDs during critical periods of brain development showed an increase in such behaviours.
"We know that early-life exposure to AEDs such as Phenobarbital triggers cell death in many brain regions associated with the onset of schizophrenia," said Guillermo Palchik, a doctoral student in the department of pediatrics at GUMC.
Fits | Epilepsy | Convulsions - Causes Symptoms Diagnosis Treatment FAQs
Fits or convulsions or Epilepsy is characterized by recurrent, involuntary seizures and is described as a chronic neurological disorder
Fits or convulsions or Epilepsy is characterized by recurrent, involuntary seizures and is described as a chronic neurological disorder
"Phenobarbital and other AEDs are not only used as a treatment for seizures but more generally in the treatment of migraines, neuropathic pain and mood disorders, among other ailments, and can be considered drugs of abuse," Palchik added.
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Neurocysticercosis / Cysticercosis of Brain / Pork Tapeworm - Causes Symptoms Diagnosis Treatment FAQs
Neurocysticercosis or Cysticercosis of brain is the most common cause of epilepsy and the most common parasitic infection of the brain. Neurocysticercosis is more common in the developing countries.
Neurocysticercosis or Cysticercosis of brain is the most common cause of epilepsy and the most common parasitic infection of the brain. Neurocysticercosis is more common in the developing countries.
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The most common gene for a syndrome associated with abnormal heart rhythms and sudden death triggers epileptic seizures and could explain sudden unexplained...
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