Sperm Grown from Skin Cells Dawns Hope On New Infertility Treatments

by Reshma Anand on  February 26, 2016 at 4:10 PM Research News
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A new method of conception raises hopes for treating infertility problems in humans. Researchers have created rudimentary mouse sperm from stem cells with which on fertilization has resulted in healthy newborn mice.
Sperm Grown from Skin Cells Dawns Hope On New Infertility Treatments
Sperm Grown from Skin Cells Dawns Hope On New Infertility Treatments

The experiment was conducted by a team of Chinese researchers from the Nanjing Medical University and their findings were published in the Journal Cell Stem Cell.

Scientists first isolated embryonic mouse stem cells and created primordial germ cells (PGC), a precursor to sperm and eggs. Then testicular tissue from newborn mice and other molecules were added to these primordial germ cells. After a period of 14 days, they developed into spermatids, non-motile sperms through meiosis. These spermatids were fertilized with eggs to produce nine baby mice.

Dr.Jiahao Sha, who co-led the research, said, "If proven to be safe and effective in humans, our platform could potentially generate fully functional sperm for artificial insemination or in-vitro fertilization techniques. Because currently available treatments do not work for many couples, we hope that our approach could substantially improve success rates for male infertility."

Source: Medindia

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