A simple ultrasound-based therapy may prevent acute kidney injury that arises after major surgery, shows research.
Mark Okusa, MD, Joseph Gigliotti, PhD, University of Virginia, and their colleagues found that a drug-free, noninvasive, ultrasound-based treatment could prevent acute kidney injury in mice.
When they exposed anesthetized mice to ultrasound with a routine clinical imaging system 24 hours prior to blood disruption to the kidneys, the mice exhibited preserved kidney health after blood flow was restored.
In contrast, sham-treated mice exhibited significant kidney injury. Further analyses revealed that the ultrasound treatment likely stimulated an anti-inflammatory response that originated from the spleen and was responsible for protecting the kidneys.
The study is published in Journal of the American Society of Nephrology (JASN).