The Hubble Space Telescope went into orbit in 1990. Shortly after that, it was discovered that the craft had blurred vision.
Fortunately, Space Shuttle astronauts were able to remedy the problem a few years later with supplemental optics. Now, a team of Italian researchers has performed a similar sight-correcting feat for a microscope imaging technique designed to explore a universe seemingly as vast as Hubble's but at the opposite end of the size spectrum—the neural pathways of the brain.
"Our system combines the best feature of one microscopy technique—high-speed, single-plane imaging of multiple sections of a sample—with a second method that eliminates the accompanying problem of scattered background light leading to blurriness," says Francesco Pavone, leader of a collaborative team from six Italian research agencies and one of the authors of a paper describing the advance that is published today in the Optical Society's (OSA) open-access journal Optics Express.