Meperidine is an opioid analgesic that is commonly used to control shivering in accidental or therapeutic hypothermia. This drug has previously been linked to increased seizure risk. However, a new study finds little published evidence to support this risk.
The authors concluded, "While use of meperidine for pain relief has declined, its role as an effective anti-shivering agent should continue to be explored." The study is published in Therapeutic Hypothermia and Temperature Management.
‘Meperidine has previously been linked to increased seizure risk. A review of medical literature suggested few cases of meperidine-associated seizures. In many of the cases, coexisting illnesses, conditions, or other factors were responsible for the increased risk of seizures.’
AdvertisementThe research team reviewed 45 years of medical literature and found relatively few cases of meperidine-associated seizures. In many of the cases, coexisting illnesses, conditions, or other factors could have contributed to or explained the increased risk of seizures.
P Novel Approach Using Bumetanide Helps Prevent Epilepsy in Newborn Mice Tiotropium and Olodaterol in COPD: Disadvantages in Some, Advantages in Others M
You May Also Like