Scientists Reveal the Mechanism Underlying Hippocampal Neuronal Injury After TBI

by Bidita Debnath on  July 20, 2014 at 10:37 PM Research News
RSS Email Print This Page Comment
Traumatic brain injury (TBI) causes gene expression changes in different regions of the brain.
 Scientists Reveal the Mechanism Underlying Hippocampal Neuronal Injury After TBI
Scientists Reveal the Mechanism Underlying Hippocampal Neuronal Injury After TBI

Cyclooxygenase-2, glutamate receptor-2, and platelet activating factor receptor expression levels are related to the occurrence and development of TBI. However, the precise relationship between the expression levels of these three factors and neuronal injury after TBI remains poorly understood.

Zhiqiang Li, Inner Mongolia Corps Hospital, Chinese People's Armed Police Forces, China performed a study and showed that sequential expression of cyclooxygenase-2, glutamate receptor-2, and platelet activating factor receptor in rat hippocampal neurons was similar after fluid percussion injury, i.e., the significant expression appeared at 8 and 12 hours after injury and these three factors are involved in occurrence and development of hippocampal neuronal injury.

These findings reveal the mechanism underlying hippocampal neuronal injury after TBI. These results were published in Neural Regeneration Research (Vol. 9, No. 9, 2014).

Source: Eurekalert

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions

More News on:

Athletes Foot 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook

News Category

News Archive