In fruit flies, a brain pathway that controls impulsive eating has been discovered by scientists. This finding may help explain binge eating in humans.
"We know when insects are hungry, they eat more, become aggressive and are willing to do more work to get the food," said Ping Shen, a UGA associate professor of cellular biology in the Franklin College of Arts and Sciences.
Advertisement"Little is known about the other half-the reward-driven feeding behavior-when the animal is not so hungry but they still get excited about food when they smell something great.
The fact that a relatively lower animal, a fly larva, actually does this impulsive feeding based on a rewarding cue was a surprise."
The research team led by Shen, who also is a member of the Biomedical and Health Sciences Institute, found that presenting fed fruit fly larvae with appetizing odors caused impulsive feeding of sugar-rich foods.
The findings suggest eating for pleasure is an ancient behavior and that fly larvae can be used in studying neurobiology and the evolution of olfactory reward-driven impulses.
To test reward-driven behaviors in flies, Shen introduced appetizing odors to groups of well-fed larvae. In every case, the fed larvae consumed about 30 percent more food when surrounded by the attractive odors.
But when the insects were offered a substandard meal, they refused to eat it.
"They have expectations," he said.
"If we reduce the concentration of sugar below a threshold, they do not respond anymore. Similar to what you see in humans, if you approach a beautiful piece of cake and you taste it and determine it is old and horrible, you are no longer interested," he added.
The study was recently published in the journal Cell Press.
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