Medindia

X

Scientists Discover Five New Genes Linked to Common Brain Cancer

by Sheela Philomena on  October 2, 2015 at 6:31 PM Cancer News   - G J E 4
Five new genetic variants associated with glioma have been discovered by a team of scientists.
 Scientists Discover Five New Genes Linked to Common Brain Cancer
Scientists Discover Five New Genes Linked to Common Brain Cancer
Advertisement

One variant increases the risk of developing glioblastoma, a particularly aggressive kind of glioma with an average survival of only 10-15 months after diagnosis, by almost a quarter.

Advertisement
The findings give important new evidence for an inherited susceptibility to glioma and offered potential clues for how to treat or prevent the disease.

"Our study is the largest ever conducted of the genetics of glioma -- the most common form of brain cancer -- and it provides firm evidence that susceptibility to the disease is in part inherited," said Richard Houlston, professor of molecular and population genetics at the Institute of Cancer Research here.

The team analysed DNA from more than 5,637 people who had developed glioma, and comparing it with 9,158 people without the disease.

One variant was associated with a 23 percent increased risk of glioblastoma.

The other four genetic variants were found to increase the risk of less aggressive, non-glioblastoma forms of glioma by around five percent each.

"One of the risk factors we identified is linked to quite a dramatically-increased chance of developing glioblastoma, a particularly aggressive kind of brain cancer," Houlston said.

The findings, published in the journal Nature Communications, sheds fresh light on the biology of gliomas, providing clues to why the disease develops and how it could be treated or prevented.

Source: IANS
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All