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Revealed: How Vaccine Scares Unfold

by Kathy Jones on  April 10, 2012 at 8:58 PM Research News   - G J E 4
Preventable contagious diseases, such as measles and whooping cough can make a comeback primarily due to concerns over vaccine risks.
 Revealed: How Vaccine Scares Unfold
Revealed: How Vaccine Scares Unfold
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A new study, published in PLoS Computational Biology, shows how to predict ways in which population vaccinating behavior might unfold during a vaccine scare.

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"These findings might help in evaluating and developing global immunization programs and public health policy", said Professor Chris Bauch of the University of Guelph's Department of Mathematics and Statistics.

Prof. Bauch and Samit Bhattacharyya of the University of Utah developed a mathematical, "Behavior-incidence" model based on game theory and social learning. They tested the model with real data from two infamous vaccine scares in England and Wales: the 1970s pertussis outbreak and the measles-mumps-rubella vaccine scare in the 1990s. In both cases, the publication of alleged vaccine risks was followed by a media firestorm in national newspapers, television, and radio. In light of this, the fact that it took 4-5 years for vaccine uptake to bottom out was puzzling. They found that the model could explain the patterns of the vaccine scares very well, and could also be applied predictively to the data sets.

The model captured the interplay between disease dynamics and vaccination behaviour during those episodes. One of the theoretical dynamics for the model was the phenomenon known as "herd immunity"; an entire population—including unvaccinated individuals—can be protected from infection by vaccinating only a certain percentage of the population. This suggests that immunization programs can be victims of their own success as past vaccinations drive disease incidence to such low levels that unvaccinated individuals feel no incentive to get vaccinated, creating ideal conditions for vaccine scares and thus future outbreaks.

Due to these conditions, as Prof. Bauch says, "Vaccine scares could become more common as eradication goals are approached for more vaccine-preventable diseases. Such models could help us predict how vaccine scares might unfold and assist in mitigation efforts."



Source: Eurekalert
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