Researchers Reveal Science Behind Anthrax Toxins Causing Illness and Death

Cells in 2 distinct areas of the body is being identified by researchers that are simultaneously targeted for damage by anthrax toxins, which results in illness and sometimes death.

Findings of researchers at the National Institute of Allergy and Infectious Diseases (NIAID) and the National Heart, Lung, and Blood Institute, both part of the National Institutes of Health, are based on testing in mice.

Anthrax - Bacillus - Symptoms - Diagnosis - Treatment - FAQs
Anthrax is caused by the bacterium Bacillus anthracis and spreads when the anthrax spores are inhaled, ingested, or come into contact with the skin lesion on a host.

According to researchers, however, the results may contribute to the development of anthrax treatments for humans.

Anthrax disease is caused by the bacterium Bacillus anthracis, which produces two deadly toxins: lethal toxin and edema toxin. When B. anthracis infects a human or animal, both toxins seek out and bind to receptors on the surfaces of human and animal cells.

Using two types of laboratory mice-those missing the anthrax toxin receptor on a single type of cell or those having the receptor present on a single type of cell-the scientists compared disease progression among the rodents.

New Sea Compound Helps Protect Against Anthrax
A novel compound found in an ocean microbe could pave way for effective treatment options for anthrax, says study.

They concluded that anthrax-induced death is caused primarily by lethal toxin targeting heart cells and muscle cells surrounding blood vessels, and edema toxin targeting liver cells.

The study has been published online in Nature.

Scientists Discover New Kind of Antibiotic may be More Effective at Fighting Tuberculosis, Anthrax, and Other Diseases
Thanks to a team of scientists, diseases such as tuberculosis, anthrax, and shigellosis eventually could be treated with an entirely new and more-effective kind of antibiotic.

Source-ANI

Scientists Use Dead Zebras to Understand the Spread of Anthrax In Africa
According to findings from a small study conducted in Etosha National Park in northern Namibia, scavengers might not play as key a role in spreading anthrax through wildlife populations as previously assumed.